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Transforming the understanding
and treatment of mental illnesses.


What is RAISE?

In 2008, the National Institute of Mental Health (NIMH) launched the Recovery After an Initial Schizophrenia Episode (RAISE) project. RAISE is a large-scale research initiative that began with two studies examining different aspects of coordinated specialty care (CSC) treatments for people who were experiencing first episode psychosis. One study, the RAISE Early Treatment Program (RAISE-ETP), focused on whether or not the CSC treatment worked better than care typically available in community settings. The second, the RAISE Implementation and Evaluation Study (RAISE-IES), examined the best way for clinics to start using the CSC treatment program. The two RAISE studies are no longer enrolling participants.

RAISE findings show that it is important to do the right thing at the right time. Initial papers from RAISE-IES and RAISE-ETP describe the current state of care for early psychosis in the United States and demonstrate that coordinated specialty care can be successfully delivered in community practice settings. Additional papers show that CSC is cost effective, and that clients feel that the CSC treatment is helping them. Researchers also found that CSC is more effective than usual treatment approaches, and that CSC is most effective when the client has a shorter duration of untreated psychosis. Duration of untreated psychosis (DUP) is the length of time between the beginning of psychotic symptoms and the beginning of antipsychotic treatment. In 2010-2012, the median DUP in the U.S. was 74 weeks.

Current efforts are focused on sharing information learned from the original studies and looking for additional ways to improve the lives of people experiencing first episode psychosis. RAISE researchers are exploring new areas, such as identifying ways of decreasing the duration of untreated psychosis.

The goal of RAISE was, and is, to help decrease the likelihood of future episodes of psychosis, reduce long-term disability, and help people to get their lives back on track so they can pursue their goals.

You can find a list of all of the papers from the RAISE initiative by clicking "Published Articles" on the left side of this page.