Skip to main content

Transforming the understanding
and treatment of mental illnesses.

Science News About Attention Deficit Hyperactivity Disorder (ADHD)

Image showing differences in fMRI activation between children with and without anhedonia during reward anticipation.
NIH Study Reveals Differences in Brain Activity in Children with Anhedonia

Researchers have identified changes in brain connectivity and brain activity during rest and reward anticipation in children with anhedonia, a condition where people lose interest and pleasure in activities they used to enjoy.

a somber boy wearing a backwards baseball cap looks at the camera
Understanding the Brain Mechanisms of Irritability in Youth

Researchers have identified differences in how the brains of irritable youth react to frustration, findings that could provide new paths for developing treatments for children and adolescents with severe irritability.

MRI scan of infant's brain
Inflammation in Pregnant Moms Linked to Child’s Brain Development

High levels of maternal inflammation during pregnancy have been linked to effects in children, including reduced brain circuit communications and altered long-distance brain wiring at birth, poorer cognitive function at one year – and to reduced impulse control and working memory at two years.

hippocampus PET scan
Estrogen Alters Memory Circuit Function in Women with Gene Variant

Brain scans reveal that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene. Since working memory function is often disturbed in mental disorders, such gene-hormone interactions are suspect mechanisms that may confer risk.