Science News About Brain Anatomy and Physiology

NIH-funded research uses machine learning algorithm to predict individual response to a commonly-prescribed antidepressant.

NIH-supported study finds that spatial “replay” in neurons may help rats learn how to navigate toward goals.

The NIH has announced its continued support for the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative by funding more than 180 new BRAIN Initiative awards, bringing the total 2019 budget for the program to more than $424 million.

Researchers have uncovered sex-based differences in the development of the hippocampus and amygdala—brain areas that have been implicated in the biology of several mental disorders that impact males and females differently.

On April 11-13, 2019, approximately 1,500 scientists from many disciplines will attend the fifth annual Brain Research through Advancing Innovative Neurotechnologies (BRAIN)® Initiative Investigators Meeting in Washington, DC. This open meeting provides a forum for discussing scientific developments and potential new directions, and to identify areas for collaboration and research coordination.

Researchers have identified changes in brain connectivity and brain activity during rest and reward anticipation in children with anhedonia, a condition where people lose interest and pleasure in activities they used to enjoy.

Researchers have shown that a type of magnetic resonance imaging — called neuromelanin-sensitive MRI (NM-MRI) — is a potential biomarker for psychosis. NM-MRI signal was found to be a marker of dopamine function in people with schizophrenia and an indicator of the severity of psychotic symptoms in people with this mental illness.

A new study in rodents has demonstrated, for the first time, that the brain’s cerebellum plays a role in controlling reward and social preference behavior—findings that shed light on the brain circuits critical to the affective and social dysfunction seen across multiple psychiatric disorders.

In a new study, researchers have traced the brain pathways responsible for the effects of light on learning and mood. The findings revealed that these effects are brought about by two different and distinct pathways from the retina into the brain.

A new study has revealed more about the organization and function of a brain structure—the paraventricular nucleus of the thalamus—that may serve a key role in linking stress detection to the development of adaptive behaviors.

People infected with the human immunodeficiency virus, known as HIV, display reductions in brain volume compared with people who are not infected with HIV, but now an NIMH-funded study has shed light on the course of this deterioration and shows that antiretroviral treatment started in the first few years of infection may stop these brain changes.

The National Institutes of Health released to the scientific community an unparalleled dataset from the Adolescent Brain Cognitive Development (ABCD) study.

Star-shaped support brain cells, astrocytes, growing in 3-D “organoids” in a dish develop similarly as those in human brain tissue.

The directors of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institute of Mental Health, and the National Institute of Neurological Disorders and Stroke discuss the importance of post-mortem brain donation in a joint message.

Functional connectivity magnetic resonance imaging (fcMRI) may predict which high-risk, 6-month old infants will develop autism spectrum disorder (ASD) by age 2 years.

Beginning May 31, 2017, the National Institute of Mental Health (NIMH) will launch a speaker series intended to bring together leaders in the field conducting research using non-invasive brain stimulation and functional imaging including EEG, fMRI, and transcranial magnetic stimulation (TMS).

A genetic engineering tool has disentangled seemingly hopelessly intertwined brain circuits for social fear and aggression in mice.

Big data pinpoints genetic variation linked to brain volume and risk for disorders.

The study will follow the biological and behavioral development of more than 10,000 children through adolescence into early adulthood.

Scientists have synthesized a molecule with a unique profile of highly specific pain-relieving properties and demonstrated its efficacy in mice.

Schizophrenia, autism risk gene trajectories point to shared causes

The more folding in the thinking parts of our brain, the smarter we are – to a degree.

Two of the world’s largest brain tissue banks unify efforts to collect and distribute a critical number of brain donations for important autism research.

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of – and ahead of – its other antidepressant effects.

Later evolving and maturing brain areas, which also are those most implicated in mental illness, showed gradually increasing heritability, peaking by late adolescence – the age-of-onset for most mental disorders. New findings hold promise for understanding how age plays an important role in gene-environment interactions that underlie the disorders.

A brain blueprint maps where genes are tuned on and off during mid-pregnancy—when most brain disorders such as autism and schizophrenia occur.

The hippocampus houses learning and memory—specifically the storage of knowledge of who, what, where, and when. Using a special transgenic mouse, researchers have now pinpointed a hippocampal region called CA2 that is important for social memory, the ability of animal to recognize another of the same species. Understanding this region could be useful in understanding and treating disorders characterized by altered social behaviors such as schizophrenia, bipolar disorder, and autism.

NIMH/NICHD experts explain what sparks and halts youth violence.