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Science News About Depression

Intervention Shows Promise for Treating Depression in Preschool-Aged Children

Press Release

Researchers funded by the National Institutes of Health have shown that a therapy-based treatment for disruptive behavioral disorders can be adapted and used as an effective treatment option for early childhood depression.

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NIMH to Host Twitter Chat on Teen Depression

Institute Update

On May 3, 2018, join NIMH for a Twitter chat on teen depression with experts Dr. Argyris Stringaris and Dr. Ken Towbin.

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Suspect Molecules Overlap in Autism, Schizophrenia, Bipolar Disorder

Science Update

Depression, schizophrenia and autism spectrum disorder share some of the same patterns of suspect gene expression – molecular signatures.

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NIMH Twitter Chat on Seasonal Affective Disorder

Science Update

On February 20, 2018, join NIMH for a Twitter chat on Seasonal Affective Disorder with expert Dr. Matthew Rudorfer.

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Brain’s Alertness Circuitry Conserved Through Evolution

Press Release

Using a molecular method likely to become widely adopted by the field, researchers have discovered brain circuitry essential for alertness – and for brain states more generally.

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Depression’s “Transcriptional Signatures” Differ in Men vs. Women

Science Update

Brain gene expression associated with depression differed markedly between men and women. Such divergent “transcriptional signatures” may signal divergent underlying illness processes requiring sex-specific treatments.

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Webinar: RDoC - Fear & Anxiety: From Mechanisms to Implementation

Institute Update

This November 2016 RDoC webinar highlights the role of fear and anxiety in disorders such as phobias and depression.

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Pediatrics-based Brief Therapy Outdoes Referral for Youths with Anxiety and Depression

Science Update

A streamlined behavioral therapy delivered in a pediatrics practice offered much greater benefit to youth with anxiety and depression than a more standard referral to mental health care with follow-up in a clinical trial comparing the two approaches.

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NIMH Grantee Wins One of Science’s Most Coveted Prizes

Science Update

NIMH grantee Karl Deisseroth, M.D., Ph.D., of Stanford University, has been awarded one of science’s most generous prizes. A German foundation presented the inventor of technologies that are transforming neuroscience with its 4 million euros Fresenius Prize.

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Estrogen Alters Memory Circuit Function in Women with Gene Variant

Science Update

Brain scans reveal that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene. Since working memory function is often disturbed in mental disorders, such gene-hormone interactions are suspect mechanisms that may confer risk.

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Tapping Crowd-Sourced Data Unearths a Trove of Depression Genes

Press Release

Scientists have discovered 15 genome sites – the first ever – linked to depression in people of European ancestry. But – in a twist – the researchers didn’t have to sequence anyone’s genes! Instead, they analyzed data already shared by people who had purchased their own genetic profiles via an online service and elected to participate in its research option.

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Electroconvulsive Therapy Lifts Depression, Sustains Remission in Older Adults

Science Update

An individualized program of follow-up treatment with electroconvulsive therapy (ECT) combined with an antidepressant was effective in preventing relapse in patients 60 years and older who had had a successful initial course of treatment for severe depression.

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Ketamine Lifts Depression via a Byproduct of its Metabolism

Press Release

A chemical byproduct, or metabolite, created as the body breaks down likely holds the secret to its rapid antidepressant action .

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Facebook Q&A on Electroconvulsive Therapy

Science Update

On March 17, 2016, NIMH hosts a Facebook Q&A on electroconvulsive therapy with expert Dr. Sarah Lisanby.

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A BRIGHT Technological Future for Mental Health Trials

Science Update

Is mobile mental health research the next frontier for smartphones? Based on Dr. Patricia Areán’s pioneering BRIGHTEN study, research via smartphone app is already a reality.

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Webinar Series – Office for Research on Disparities and Global Mental Health

Science Update

View the archived webinars with NIMH experts and grantees, which focus on training, research, and methodology

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NIH Joins with Women’s Organization to Debut Postpartum Depression Video

Science Update

A new video about postpartum depression marks the launch of a mental health education collaboration by two NIH Institutes and one of the nation’s largest African-American women’s organizations.

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Disorders Share Risk Gene Pathways for Immune, Epigenetic Regulation

Science Update

Risk genes for different mental disorders work through same pathways

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Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action

Press Release

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of – and ahead of – its other antidepressant effects.

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NIMH Twitter Chat on Depression and the Development of Novel Medications

Science Update

NIMH Twitter Chat on Depression and the Development of Novel Medications

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NIMH Twitter Chat on Premenstrual Dysphoric Disorder

Science Update

NIMH Twitter Chat on Premenstrual Dysphoric Disorder

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NIMH Twitter Chat on Men and Depression

Science Update

NIMH Twitter Chat on Men and Depression

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NIMH Twitter Chat on Postpartum Depression

Science Update

NIMH Twitter Chat on Postpartum Depression

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Jump-starting Natural Resilience Reverses Stress Susceptibility

Press Release

Scientists have traced vulnerability to depression-like behaviors to out-of-balance neuronal electrical activity and made mice resilient by reversing it.

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Girls Thrive Emotionally, Boys Falter After Move to Better Neighborhood

Science Update

Girls in public housing benefited emotionally from a move to a better neighborhood while boys fared worse than if they’d stayed in the poor neighborhood. Rates of depression and conduct disorder markedly increased in boys and decreased in girls. Boys also experienced significantly increased rates of post-traumatic stress disorder (PTSD), complicating housing policy decision-making.

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