Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Transforming the understanding
and treatment of mental illnesses.

Home  |  Help for Mental Illnesses

Menu

NIMH Practical Clinical Trials

NIMH designed the practical clinical trials to examine changes in both symptoms and functioning to determine whether a treatment improves quality of life, care-giving burden, or use of health services.

These "effectiveness studies" are part of a rigorous effort to discover what therapies work best. The practical clinical trials are:

  • CATIE
    Clinical Antipsychotic Trials of Intervention Effectiveness
  • STAR*D
    Sequenced Treatment Alternatives to Relieve Depression Study
  • STEP-BD
    Systematic Treatment Enhancement Program for Bipolar Disorder
  • TADS
    Treatment for Adolescents with Depression Study
  • TORDIA
    Treatment of SSRI-resistant Depression in Adolescents study

Disclaimer

We link to external websites for informational purposes only, but we do not endorse or guarantee their accuracy. Once you leave our site, you will be subject to the new website’s privacy policy. Read NIMH’s full external linking policy for more information.