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Transforming the understanding
and treatment of mental illnesses.

Funding and Policy Announcements (Complete List):NIMH-Sponsored | NIMH-Participating | Both
Program Announcements:NIMH-Sponsored | NIMH-Participating | Both
Requests for Applications:NIMH-Sponsored | NIMH-Participating | Both
Policy Announcements:NIMH-Sponsored | NIMH-Participating | Both

NIMH-Sponsored Program Announcements

Announcement Number Title Release Date Expiration Date
PAR-25-179 Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-181 Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-182 Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-183 Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-184 Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-285 Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-180 First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-177 Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-178 Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)  2024-11-26 2027-10-16
PAR-25-289 Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)  2024-11-25 2028-01-08
PAR-25-288 Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)  2024-11-25 2028-01-08
PAR-25-281 Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)  2024-11-22 2028-01-08
PAR-25-282 Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)  2024-11-22 2028-01-08
PAR-25-290 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)  2024-11-22 2028-01-08
PAR-25-291 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)  2024-11-22 2028-01-08
PAR-25-278 Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)  2024-11-21 2026-01-08
PAR-25-035 Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed)  2024-11-21 2025-09-08
PAR-25-287 Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)  2024-11-21 2028-01-08
PAR-25-286 Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)  2024-11-21 2028-01-08
PAR-25-034 Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3 Clinical Trial Optional)  2024-11-21 2025-06-21
PAR-25-038 Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)  2024-11-18 2026-09-08
PAR-25-037 Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)  2024-11-18 2026-09-08
PAR-25-065 Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-064 Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-039 Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-040 Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-067 Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-066 Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)  2024-11-18 2026-09-08
PAR-25-201 Integrating Mental Health Care into Health Care Systems and Non-Health Settings in Low- and Middle-Income Countries (R01 Clinical Trial Optional)  2024-11-08 2028-01-08
PAR-25-136 Laboratories to Optimize Digital Health (R01 Clinical Trial Required)  2024-11-07 2028-01-08
PAR-25-063 Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)  2024-11-06 2026-05-08
PAR-25-036 Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)  2024-11-06 2026-05-08
PAR-25-207 Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)  2024-10-31 2028-01-08
PAR-25-206 Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)  2024-10-31 2028-01-08
PAR-24-240 Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U01 Clinical Trial Not Allowed)  2024-07-10 2026-02-14
PAR-24-250 Standardizing Data and Metadata from Wearable Devices (R01 Clinical Trial Not Allowed)  2024-07-02 2026-06-11
PAR-24-233 NIMH Research Education Mentoring Program for HIV Researchers (R25 Clinical Trial Not Allowed)  2024-06-27 2026-09-08
PAR-24-165 AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)  2024-03-22 2026-08-26
PAR-24-164 Developmental AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)  2024-03-22 2026-08-26
PAR-24-118 Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)  2024-02-08 2025-01-08
PAR-24-024 Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)  2023-06-30 2025-01-08
PAR-24-025 Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)  2023-06-30 2025-01-08
PAR-24-023 Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)  2023-06-29 2025-01-08
PAR-24-026 Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)  2023-06-29 2025-01-08
PAR-24-210 Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)  2023-06-20 2026-05-19
PAR-23-207 Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)  2023-06-14 2025-01-07
PAR-23-208 Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)  2023-06-14 2025-01-07
PAR-23-149 Mentored Career Transition Award for Intramural Fellows (K22 Clinical Trials Not Allowed)  2023-04-20 2026-03-13
PAR-23-150 Mentored Career Transition Award for Intramural Fellows (K22 Clinical Trials Required)  2023-04-20 2026-03-13
PAR-23-168 Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)  2023-04-17 2025-01-07
PAR-23-165 Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Not Allowed)  2023-04-07 2025-01-08
PAR-23-164 Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)  2023-04-07 2025-01-07
PAR-23-263 NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)  2023-03-03 2025-05-26
PAR-23-266 NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed)  2023-03-03 2025-05-26
PAR-23-265 NIMH Short Courses for Mental Health Related Research (R25 -Independent Clinical Trial Not Allowed)  2023-03-03 2025-05-26
PAR-23-105 Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)  2023-01-13 2025-05-08
PAR-23-101 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)  2023-01-13 2025-01-08
PAR-23-060 Formative and Pilot Intervention Research to Optimize HIV Prevention and Care Continuum Outcomes (R34 Clinical Trial Optional)  2023-01-10 2026-01-10
PAR-23-062 Innovations to Optimize HIV Prevention and Care Continuum Outcomes (R01 Clinical Trial Optional)  2023-01-10 2026-01-10
PAR-23-061 Innovations to Optimize HIV Prevention and Care Continuum Outcomes (R21 Clinical Trial Optional)  2023-01-10 2026-01-10
PAR-23-091 Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed)  2023-01-06 2025-01-08
PAR-23-095 Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)  2023-01-06 2025-01-08
PAR-23-096 Laboratories to Optimize Digital Health (R01 Clinical Trial Required)  2023-01-06 2025-01-08
PAR-23-093 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)  2023-01-06 2025-01-08
PAR-23-050 Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)  2022-12-13 2025-01-08
PAR-22-170 Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed)  2022-07-07 2025-09-08
PAR-22-155 Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)  2022-05-26 2025-06-10
PAR-22-172 Mental Health Research Dissertation Grant to Enhance Workforce Diversity (R36 Independent Clinical Trial Not Allowed)  2022-05-25 2025-05-08
PAR-22-143 National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders or Alcohol Use Disorder (U01 Clinical Trial Optional)  2022-05-06 2025-02-25
PAR-22-144 National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders or Alcohol Use Disorder (U19 Clinical Trial Optional)  2022-05-06 2025-02-25
PAR-22-137 Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed)  2022-03-15 2025-01-08
PAR-22-138 Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed)  2022-03-15 2025-01-08
PAR-22-031 Drug Discovery For Nervous System Disorders (R01 Clinical Trials Not Allowed)  2021-11-29 2025-01-08
PAR-22-032 Drug Discovery For Nervous System Disorders (R21 Clinical Trials Not Allowed)  2021-11-29 2025-01-08
PAR-22-067 Basic Neurodevelopmental Biology of Circuits and Behavior (R21 Clinical Trial Not Allowed)  2021-11-19 2025-01-08
PAR-22-066 Basic Neurodevelopmental Biology of Circuits and Behavior (R01 Clinical Trial Not Allowed)  2021-11-16 2025-01-08
PAR-22-039 Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)  2021-10-12 2025-01-08
PAR-22-038 Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)  2021-10-12 2025-01-08
PAR-21-239 NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 No Independent Clinical Trials)  2021-07-08 2025-01-08
PA-21-235 NIMH Exploratory/Developmental Research Grant (R21 Clinical Trial Not Allowed)  2021-05-10 2025-01-08
PA-21-201 Research on Autism Spectrum Disorders (R01 Clinical Trial Optional)  2021-03-31 2025-01-08
PAR-21-175 Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity (R01 Clinical Trial Optional)  2021-03-18 2025-01-08
PAR-21-176 Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity (R21 Clinical Trial Optional)  2021-03-18 2025-01-08