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Small Business Research

The I-Corps at NIH Program is now accepting applications for the first cohort of 2020. Applications are due October 22, 2019.

NIMH SBIR/STTR Program Staff are committed to working with applicants and awardees to support research and development of innovative technologies by small businesses that have the potential to succeed commercially or to provide significant societal benefits, in the areas of neuroscience and mental health.

Program staff encourage potential applicants to contact us in the early stages of application planning to determine programmatic fit and to provide support in preparing a strong application. Please e-mail a draft Specific Aims page to help us connect you with the appropriate staff and ensure efficient communication.

We also encourage investigators to explore the website and reach out to us to learn more about what the SBIR/STTR programs have to offer.

What are the NIMH SBIR & STTR programs?

The Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) Programs are one of the largest sources of early-stage capital for technology commercialization in the United States. These small business programs support research and development by small businesses of innovative technologies that have the potential to succeed commercially or provide significant societal benefits.

The goals of the SBIR & STTR programs at the National Institute of Mental Health (NIMH) is to support small businesses to develop technologies that can advance the mission of the Institute, including basic neuroscience research, translational and clinical research, clinical diagnosis and treatment, and dissemination and implementation of evidence-based research on mental disorders.

Difference between SBIR and STTR

SBIR Program

  • The Principal Investigator must be primarily employed with the small business concern at the time of award and for the duration of the project period

STTR Program

  • The Principal Investigator may be primarily employed by either the small business concern or the collaborating non-profit research institution at the time of award and for the duration of the project period
  • Requires that the small business concern formally collaborate with a non-profit research institution
    • The small business must perform at least 40% of the work
    • The research institution must perform at least 30% of the work

Research Topics of Interest

The SBIR/STTR program is a source of support for the research and development of technologies that correspond to the following identified research priorities:

In addition, NIMH lists priority SBIR/STTR topics in specific NIMH SBIR/STTR FOAs, and in the SBIR/STTR Program Descriptions and Research Topics Document.