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Science News from 2022

Open pill bottle with blue PrEP pills spilling out
Barriers and Supports to HIV Prevention Among Young Women in Kenya

In a qualitative study supported by NIMH, researchers identified barriers and supports to Kenyan women’s use of PrEP, a highly effective medication to reduce HIV transmission.

Close up of a T cell being infected by the HIV virus on its surface
T Cells Help HIV Enter and Persist in the Brain

A recent NIMH-supported study sheds light on the role of a unique set of T cells in trafficking HIV infection into the brain and mediating the virus’ persistence there.

DNA strand beside a side profile of a head with the brain illuminated, on an abstract digital background
Researchers Map the Genetic Landscape of Schizophrenia in the Brain

In a comprehensive postmortem genetic analysis of the caudate nucleus in the brain, NIMH-supported researchers identified many genes associated with schizophrenia risk, including a gene that regulates the flow of the chemical messenger dopamine.

Dr. Elisabeth Murray featured image
Dr. Elisabeth Murray Honored With Mika Salpeter Lifetime Achievement Award

Dr. Elisabeth A. Murray has been honored with the 2022 Mika Salpeter Lifetime Achievement Award from the Society for Neuroscience recognizing her distinguished career in biomedical research and dedication to mentoring future leaders in neuroscience.

A digital recreation of a DNA strand.
Rare Genetic Variation in 10 Genes Substantially Raise the Risk for Schizophrenia

In one of the largest genetic studies of its kind researchers funded by the National Institute of Mental Health identified variations in 10 genes that significantly raise the risk for schizophrenia—information that could help identify new treatment targets.

Illustration of multicolored hands around a globe
Media Advisory: NIH’s Climate and Health Initiative Tackles Global Health Effects Associated With a Climate change

A coalition of leaders at NIH outline how the NIH Climate Change and Health Initiative is uniquely poised to lead and engage with communities and agencies globally to address the health effects associated with climate change.

Two diverse pairs of hands cupped under a lightbulb illuminating a digital space.
NIMH Turns Challenges into Opportunities

The recent NIMH Mental Health Services Research conference covered a range of topics, including mental health equity, policy, and funding.

Example of a transplanted human cortical organoid (t-hCO) in the rat cortex. Credit: Revah, O. et al. Nature (2022); Pasca Lab, Stanford
Researchers Develop Method to Study Brain Connectivity, Functionality

Scientists have developed a research method that allows for a much more detailed examination of the brain processes involved in some neurological and mental disorders.

A father and son sitting on a park bench.
Family-Based Intervention Lowers Long-Term Suicide Risk in Youth

In a recent study supported by the National Institute of Mental Health, researchers examined the impact of a family-based intervention on suicide risk in youth and found risk-reduction benefits up to 10 years later.

Winners of 2022 Speaking Up About Mental Health
NIH Announces Winners of High School Mental Health Essay Contest

The National Institutes of Health (NIH) is pleased to announce the winners of 2022 Speaking Up About Mental Health! This Is My Story essay contest.

Illustration of neuronal connections.
NIH BRAIN Initiative Launches Projects to Develop Cell Atlases and Molecular Tools for Cell Access

The National Institutes of Health has launched two transformative projects supported by the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative: The BRAIN Initiative® Cell Atlas Network and the Armamentarium for Precision Brain Cell Access.

A photograph of Dr. Borba.
Dr. Christina P.C. Borba Named Director of Office for Disparities Research and Workforce Diversity

The National Institute of Mental Health has appointed Christina P.C. Borba, Ph.D., M.P.H., as director of the Office for Disparities Research and Workforce Diversity (ODWD). She began her new role on September 6, 2022.

A row of abstract circles in various colors
NIH Awards $100 Million for Autism Centers of Excellence Program

The National Institutes of Health has awarded a total of $100 million over the next five years to support nine Autism Centers of Excellence. This endeavor funds large research projects to understand and develop interventions for autism spectrum disorder.

Close up of a female doctor’s hands filling out a screening form while speaking with a patient
A Clinical Pathway for Suicide Risk Screening in Adult Primary Care

An NIMH-supported workgroup developed an evidence-based screening pathway to help primary care doctors identify adults at risk of suicide and bridge them to critical mental health services.

Abstract image of program code being analyzed
Computational Methods Identify Psychosis Symptoms in Spoken Language

Researchers used computational methods to automatically detect abnormalities in spoken language that could be used to predict symptoms of psychotic disorders including schizophrenia.

Father sitting and talking to his toddler
Toddlers’ Responses to “Baby Talk” Linked to Social, Cognitive, Language Abilities

In an NIMH-supported study, researchers found that toddlers respond to emotionally expressive speech in different ways, and these varied responses are linked with their social, linguistic, and cognitive abilities.

Young child resting against a swing
Low Motivation for Social Bonding May Signal Behavior Problems in Early Childhood

In an NIMH-supported study, researchers found that low social affiliation—low motivation for social engagement and bonding—may be a precursor that identifies children as early as age 2 who are likely to develop callous-unemotional behaviors.

A teen (in background) pushes away a plate with broccoli on it (in foreground).
Adult “Picky Eaters” Recall Helpful Parent Feeding Strategies

Researchers asked a group of self-identified adult “picky eaters” to reflect on their parents’ feeding strategies to better understand which strategies were helpful and which weren’t.

Picture of Dr. Karen Lincoln
Dr. Karen Lincoln Wins the 2022 James Jackson Memorial Award

Dr. Karen D. Lincoln wins the 2022 NIMH James Jackson Memorial Award in recognition of her excellence in mental health disparities research, mentorship, and community engagement.

Photograph of a man staring straight ahead with the sides of his face blurry and out of focus
Feelings of Detachment After Trauma May Signal Worse Mental Health Outcomes

A new NIMH-supported study shows that experiencing persistent feelings of detachment following trauma is an early psychological and biological marker of worse mental health outcomes.

Kids in classroom raising hands.
Study Furthers Understanding of Disparities in School Discipline

A new NIMH-supported analysis shows that disciplinary disparities occur as early as preschool and that their effects can negatively influence how well students do in later years.

A mental health provider talks with a veteran.
Study Shows REACH VET Program Effective for Veterans at High Risk for Suicide

A recent NIMH co-authored study shows that a Department of Veterans Affairs suicide prevention program was associated with fewer inpatient mental health admissions and emergency department visits, and a 5 percent reduction in documented suicide attempts.

Hands typing at a computer
Mindful Mood Balance Effective for Treating Residual Depressive Symptoms and Suicidal Ideation

NIMH-supported researchers have found an online mindfulness-based cognitive behavioral therapy—called Mindful Mood Balance—is effective at reducing residual depressive symptoms and at reducing suicidal ideation in those who experience these symptoms.

A mother and toddler with a health care provider
Multistage Autism Screening in Early Intervention Settings May Reduce Disparities

An NIMH-supported study shows that incorporating a multistage screening process for autism spectrum disorder (ASD) into federally funded early intervention services may reduce disparities in early ASD diagnosis.

A drawing of parapinopsin, a photoswitchable GPCR that can be turned on using UV light and turned off using amber light. Credit: Copits, B. et al., (2021). A photoswitchable GPCR-based opsin for presynaptic inhibition. Neuron, 109(11), 1791–1809.e11.
Tool Uses Light to Inhibit Neural Activity in Mice

Researchers supported by NIH have developed a way to genetically insert a type of light receptor into neurons. The new technique enables the researchers to suppress the neuron’s activity using pulses of light.

Illustrated human head with red spot in the center
New Approach Allows Magnetic Brain Stimulation to Target Deep Brain Structures

TMS can only directly stimulate the outermost layer of the brain, but NIMH researchers have found that mapping a person’s brain architecture may make it possible to guide TMS to deep brain targets.

3D rendering of a molecule
Autism and Congenital Heart Disease Share Underlying Molecular Network

A recent study of gene networks may hold some promising clues about shared mechanisms underlying autism spectrum disorder and congenital heart disease, two physiologically distinct disorders that often co-occur.

The National Institutes of Health invites students ages 16 to 18 years old to participate in the “2022 Speaking Up About Mental Health!” essay contest.
National Contest Encourages High School Students to Write Short Essays Exploring Mental Health

The National Institutes of Health invites students ages 16 to 18 years old to participate in the “2022 Speaking Up About Mental Health!” essay contest.

A doctor wearing a white lab coat and stethoscope facing a male patient wearing a white and blue flannel shirt.
Clinical Decision Support System Reduces Cardiovascular Risk in Patients With Serious Mental Illness

A new study shows the use of a clinical decision support system to prompt the use of shared decision-making tools, such as handouts, may result in positive impacts on long-term cardiovascular health in patients with serious mental illness.

Enhanced photo of researchers standing and wearing virtual reality headsets to plan DBS implantation.
Personalizing Deep Brain Stimulation for Treatment-Resistant Depression

A recent NIMH-supported study investigated whether deep brain stimulation could be personalized for individuals with treatment-resistant depression.

Woman having her blood pressure measured
Women’s Experiences of Sexual Assault and Harassment Linked With High Blood Pressure

Women who had ever experienced sexual violence in their lifetime—including sexual assault and workplace sexual harassment—were more likely to develop high blood pressure over a seven-year follow-up period, according to an NIH-funded study.

A close-up view of an adult man’s face and eye
Machine Learning Study Sheds Light on Gaze Patterns in Adults With Autism

NIMH researchers examine what people with ASD and people without ASD look at when viewing a social scene.

Portrait shot of Dr. Robert Heinssen
Dr. Robert Heinssen to Step Down as DSIR Director

In June 2022, Robert Heinssen, Ph.D., ABPP, will step down as director of the NIMH Division of Services and Intervention Research (DSIR) and transition to a new role as a senior advisor in the NIMH Office of the Director.