Skip to content

NIMH RDoC Publications

Browse publications about the Research Domain Criteria (RDoC), an NIMH initiative. RDoC is a research framework designed for studying the full range of human behavior from normal to abnormal based on biology, behavior, and context.

2018

National Advisory Mental Health Council Workgroup on Changes to the Research Domain Criteria Matrix (2018). RDoC Changes to the Matrix (CMAT) Workgroup Update: Proposed Positive Valence Domain Revisions. Bethesda, MD.

2017

Clark LA, Cuthbert B, Lewis-Fernández R, Narrow WE, Reed GM. Three Approaches to Understanding and Classifying Mental Disorder: ICD-11, DSM-5, and the National Institute of Mental Health’s Research Domain Criteria (RDoC). Psychological Science in the Public Interest. 2017 Sep;18(2):72-145. PMID: 29211974

Garvey MA, Cuthbert BN. Developing a Motor Systems Domain for the NIMH RDoC Program. Schizophr Bull. 2017 Sep 1;43(5):935-936. doi: 10.1093/schbul/sbx095. PMID: 28911051

Vaidyanathan U, Pacheco J. Research Domain Criteria Constructs: Integrative reviews and empirical perspectives. J Affect Disord. 2017 Jul;216:1-2. doi: 10.1016/j.jad.2017.05.028. PMID: 28610708

2016

Morris SE, Vaidyanathan U, Cuthbert BN. Changing the diagnostic concept of schizophrenia: the NIMH research domain criteria initiative. In The Neuropsychopathology of Schizophrenia 2016 (pp. 225-252). Springer International Publishing. PMID: 27627829

National Advisory Mental Health Council Workgroup on Tasks and Measures for Research Domain Criteria (2016). Behavioral Assessment Methods for RDoC Constructs. Bethesda, MD.

Sanislow CA. Connecting psychopathology meta-structure and mechanisms. J Abnorm Psychol. 2016 Nov;125(8):1158-1165. PMID: 27819475

Sanislow CA. Updating the Research Domain Criteria. World Psychiatry. 2016 Oct;15(3):222-223. doi: 10.1002/wps.20374. PMID: 27717261

Cuthbert BN. The NIMH Research Domain Criteria Project: Research Domain Criteria and global mental health. In M. State, BL. Miller, & T. Lehner (Eds). Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. Cambridge, MA: Academic Press; 2016 Jun 7. (pp. 397 – 410).

Kozak MJ, Cuthbert BN. The NIMH Research Domain Criteria Initiative: Background, issues, and pragmatics. Psychophysiology. 2016 Mar;53(3):286-97. doi:10.1111/psyp.12518. PMID: 26877115

Garvey M, Avenevoli S, Anderson K. The National Institute of Mental Health Research Domain Criteria and Clinical Research in Child and Adolescent Psychiatry. J Am Acad Child Adolesc Psychiatry. 2016 Feb;55(2):93-8. doi: 10.1016/j.jaac.2015.11.002. PMID: 26802775

Goldstein AB, Morris SE. Reconceptualizing Prevention: Commentary on “Conducting Psychopathology Prevention Research in the RDoC Era”. Clinical Psychology: Science and Practice. Epub: 2016 Feb 16. DOI: 10.1111/cpsp.12143

2015

Morris SE, Vaidyanathan U, Cuthbert BN. Psychophysiological science and the research domain criteria: A commentary. Int J Psychophysiol. 2015 Nov;98(2 Pt 2):378-80. doi: 10.1016/j.ijpsycho.2015.11.002. PMID: 26546860

Vaidyanathan U, Vrieze SI, Iacono, WG. The power of theory, research design, and transdisciplinary integration in moving psychopathology forward. Psychol Inq. 2015; 26(3): 209-230. doi:10.1080/1047840X.2015.1015367

Cuthbert BN. Research Domain Criteria: Toward future psychiatric nosologies. Dialogues Clin Neurosci. 2015 Mar;17(1):89-97. PMID: 25987867

Sanislow CA, Quinn KJ, Sypher I. NIMH Research Domain Criteria (RDoC) (2015). In (R. L. Cautin & S. O. Lilienfeld, Eds.) The Encyclopedia of Clinical Psychology. Hoboken, NJ: Wiley-Blackwell. 2015.

2014

Cuthbert BN. Translating intermediate phenotypes to psychopathology: the NIMH Research Domain Criteria. Psychophysiology. 2014 Dec;51(12):1205-6. doi: 10.1111/psyp.12342. PMID: 25387702 

Ford JM, Morris SE, Hoffman RE, Sommer I, Waters F, McCarthy-Jones S, Thoma RJ, Turner JA, Keedy SK, Badcock JC, Cuthbert BN. Studying Hallucinations Within the NIMH RDoC Framework. Schizophr Bull. 2014 Jul;40 (Suppl 4):S295-304. PMID: 4141312

Cuthbert BN. Response to Lilienfield, Behaviour Research and Therapy. Behav Res Ther. 2014 Nov;62:140-2. PMID: 25294624

Casey BJ, Oliveri ME, Insel T. A neurodevelopmental perspective on the Research Domain Criteria (RDoC) framework. Biol Psychiatry. 2014 Sep 1; 76(5): 350-3. PMID: 25103538

Etkin A, Cuthbert B. Beyond the DSM: Development of a transdiagnostic psychiatric neuroscience course. Acad Psychiatry. 2014 Apr; 38(2): 145-50. PMID: 24493358

Cuthbert BN. Research domain criteria: Toward future psychiatric nosology. Asian Journal of Psychiatry. 2014; 7:4-5.

Cuthbert BN. NIMH RDoC Workgroup. The RDoC framework: Continuing commentary. World Psychiatry. 2014 Jun; 13(2): 196-7. PMCID: PMC4102294

Cuthbert BN. The RDoC framework: Facilitating transition from ICD/DSM to approaches that integrate neuroscience and psychopathology. World Psychiatry. 2014 Feb; 13(1): 28-35. PMCID: PMC2918011

Simmons JM, Quinn KJ. The NIMH Research Domain Criteria (RDoC) Project: Implications for genetics research. Mamm Genome. 2014 Feb;25(1-2): 23-31.PMID: 24085332

Morris SE, Rumsey JM, Cuthbert BN. Rethinking mental disorders: the role of learning and brain plasticity. Restor Neurol Neurosci. 2014;32(1): 5-23. PMID: 23902986

2013

Cuthbert BN, Kozak MJ. Constructing constructs for psychopathology: The NIMH research domain criteria. J Abnorm Psychol. 2013 Aug;122(3):928-37. PMID: 24016027

Cuthbert BN, Insel TR. Toward the future of psychiatric diagnosis: the seven pillars of RDoC. BMC medicine. 2013;11:126. PMCID: PMC3653747

2012

Morris SE, Cuthbert BN. Research Domain Criteria: Cognitive systems, neural circuits, and dimensions of behavior. Dialogues Clin Neurosci. 2012 Mar;14(1):29-37. PMCID: PMC3341647

2010

Cuthbert B, Insel T. The data of diagnosis: New approaches to psychiatric classification. Psychiatry. 2010 Winter;73(4):311-314. PMID: 21198381

Sanislow CA, Pine DS, Quinn KJ, Kozak MJ, Garvey MA, Heinssen RK, Wang PS, Cuthbert BN. Developing constructs for psychopathology research: Research domain criteria. J Abnorm Psychol. 2010 Nov;119(4):631-9. PMID: 20939653

Cuthbert BN, Insel TR. Toward new approaches to psychotic disorders: The NIMH Research Domain Criteria project. Schizophr Bull. 2010 Nov;36(6):1061-2. Epub 2010 Oct 7. PMCID: PMC2963043

Cuthbert BN, Insel TR. New directions in diagnosis: Research domain criteria and global mental health. In E. Sorel (Ed.), 21st century global mental health. Burlington, MA: Jones & Bartlett. 2010. (pp. 55-70).

Insel T, Cuthbert B, Garvey M, Heinssen R, Pine DS, Quinn K, Sanislow C, Wang P. Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010 Jul;167(7):748-51. PMID: 20595427

Cuthbert, BN & Insel, TR. Classification issues in women's mental health: Clinical utility and etiological mechanisms. Arch Womens Ment Health. 2010 Feb;13(1):57-9. PMID: 20058041

2009

Insel, TR & Cuthbert, BN. Endophenotypes: Bridging genomic complexity and disorder heterogeneity. Biological Psychiatry. 2009 Dec 1;66(11), 988-9. PMID: 19900610