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Molecular Imaging Branch (MIB)

2014 Publications

Full Refereed Papers

1. Tsujikawa T, Zoghbi SS, Hong J, Donohue SR, Jenko KJ, Gladding RL, Halldin C, Pike VW, Innis RB, Fujita M, In vitro and in vivo evaluation of [11C]SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors. NeuroImage, 2014, 84, 733-741. DOI: 10.1016/j.neuroimage.2013.09.043, PMID: 24076222 .

2. Al-Huniti MH, Lu SY, Pike VW, Lepore SD, Enhanced nucleophilic fluorination and radiofluorination of organosilanes appended with potassium-chelating leaving groups. J. Fluorine Chem., 2014, 158, 48-52.  DOI: 10.1016/j.fluchem.2013.12.005, PMID: 24653526 .

3. Shrestha S, Liow J-S, Jenko K, Lu SY, Gladding RL, Svenningsson P, Zoghbi SS, Morse CL, Pike VW, Innis RB, [11C]CUMI-101, a positron emission tomographic radioligand, behaves as a serotonin 1A receptor antagonist and also binds to alpha1A receptors in brain. J. Nucl. Med., 2014, 55, 141-146. DOI: 10.2967/jnucmed.113.125831, PMID: 24385311 .

4. Lohith TG, Zoghbi SS, Morse CL, Ferraris-Araneta MD, Barth VN, Goebl NA, Tauscher JT, Pike VW, Innis RB, Fujita M, Retest imaging of [¹¹C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in brain of healthy humans. NeuroImage, 2014, 87, 89-95. DOI: 10.1016/j.neuroimage.2013.10.068, PMID: 24225488 .

5. Shrestha S, Nelson EE, Liow J-S, Gladding R, Lyoo CH, Noble PL, Morse C, Henter ID, Kruger J, Zhang B, Suomi SJ, Svenningsson P, Pike VW, Winslow JT, Leibenluft E, Pine DS, Innis RB, Fluoxetine administered to monkeys: Effects on the serotonin transporter and behavior. Am. J. Psychiatry, 2014, 171, 323-331.  DOI: 10.1176/appi.ajp.2013.13020183, PMID: 24480874 .

6. Lodge NJ, Li Y-W, Chin FT, Dischino DD, Zoghbi SS, Deskus JA, Mattson RJ, Imaizumo M., Pieschl R, Molski TF, Fujita M, Zaczek R, Macor JE, Bronson JJ, Dulac H, Innis RB, Pike VW, Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors. Nucl. Med. Biol., 2014, 41, 524-535. DOI: 10.1016/j.nucmedbio.2014.03.005, PMID: 24793011 .

7. Lyoo CH, Zanotti-Fregonara P, Zoghbi SS, Liow J-S, Xu R, Pike VW, Zarate Jr, CA, Fujita M, Innis RB, Image-derived input function derived from a supervised clustering algorithm: methodology and validation in a clinical protocol using [11C](R)-rolipram. Plos One, 2014, 9, e89101.  DOI:10.1371/journal.pone.0089101, PMID: 24586526 .

8. Brouwer C, Jenko K, Zoghbi SS, Innis RB, Pike VW, Development of N-methyl-(2-arylquinolin-4-yl)oxypropanamides as leads to PET radioligands for translocator protein (18kDa). J. Med. Chem., 2014, 57, 6240-6251. DOI: 10.1021/jm5007947, PMID: 24949670 .

9. Lohith TG, Xu R, Tsujikawa T, Morse CL, Anderson KB, Gladding RL, Zoghbi SS, Fujita M, Innis RB, Pike VW, Evaluation in monkey of two candidate PET radioligands, [11C]RX-1 and [18F]RX-2, for imaging brain 5-HT4 receptors. Synapse, 2014, 68, 613-623. DOI 10.1002/syn.21773, PMID: 25088028 .

10. Zanotti-Fregonara P, Zhang Y, Jenko KJ, Gladding RL, Zoghbi SS, Fujita M, Sbardella G, Castellano S, Taliani S, Martini C, Innis RB, Da Settimo F, Pike VW, Synthesis and evaluation of TSPO PET radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971. ACS Chem. Neurosci., 2014, 5, 963-971. DOI: 10.1021/cn500138n, PMID: 25123416 .