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Molecular Imaging Branch (MIB)

2019 Publications

Full Refereed Papers

S. Paul, M.B. Haskali, J.S. Liow, S.S. Zoghbi, V.N. Barth, M.C. Kolodrubetz, M.R. Bond, C.L. Morse, R.L. Gladding, M.P. Frankland, N. Kant, L. Slieker, S. Shcherbinin, H.N. Nuthall, P. Zanotti-Fregonara, J.A. Hanover, C. Jesudason, V.W. Pike, R.B. Innis. Evaluation of a novel PET radioligand to image O-GlcNAcase in brain and periphery of rhesus monkey and knock-out mouse. J. Nucl. Med. (2019) 60, 129-134. DOI:10.2967/jnumed.118.213231. 

S. Paul, E. Gallagher, J.S. Liow, S. Mabins, K. Henry, S.S. Zoghbi, R.N. Gunn, W.C. Kreisl, E.M. Richards, P. Zanotti-Fregonara, C.L. Morse, J. Hong, A. Kowalski, V.W. Pike, R.B. Innis, M. Fujita. Building a database for brain 18 kDa translocator protein imaged using [11C]PBR28 in healthy subjects. J. Cereb. Blood Flow Metab. (2019) 39, 1138-1147. DOI:10.1177/0271678X18771250. 

A. Lindberg, S. Lu, S. Nag, M. Schou, J.S. Liow, S.S. Zoghbi, M.P. Frankland, R.L. Gladding, C.S. Elmore, R.B. Innis, C. Halldin, V.W. Pike, Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors. Nucl. Med. Biol. (2019) 70, 1-13. DOI:10.1016/j.nucmedbio.2019.01.005. 

M.J. Kim, M. McGwier, K.J. Jenko, J. Snow, C. Morse, S.S. Zoghbi, V.W. Pike, R.B. Innis, W.C. Kreisl, Neuroinflammation in frontotemporal lobar degeneration revealed by 11C-PBR28 PET. Ann. Clin. Trans. Neurol. (2019) 6, 1327-1331. DOI:10.1002/acn3.50802. 

C. Taddei, V.W. Pike, [11C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years. EJNMMI Radiopharm. Chem. (2019) 4, Article ID 25. (Prize for best basic science paper) DOI:10.1186/s41181-019-0073-4. 

A. Lindberg, R. Arakawa, T. Nogam, S. Nag, M. Schou, C.S. Elmore, L. Farde, V.W. Pike, C. Halldin, Potential for imaging the high-affinity state of the 5-HT1B receptor: a comparison of three PET radioligands with differing intrinsic activity. EJNMMI Res. (2019) 9, Article ID 100. DOI:10.1186/s13550-019-0570-1. 

A. Lindberg, S. Nag, M. Schou, R. Arakawa, T. Nogami, M.M. Moein, C.S. Elmore, V.W. Pike, C. Halldin, Development of a 18F-labeled PET radioligand for imaging 5-HT1B receptors: [18F]AZ10419096. Nucl. Med. Biol. (2019) 78, 11-16. DOI:10.1016/j.nucmedbio.2019.10.003. 

B.Y. Yang, S. Telu, M.B. Haskali, C.L. Morse, V.W. Pike, A gas phase route to [18F]fluoroform with limited molar activity dilution. Sci. Reports (2019) 16, Article ID 14835. DOI:10.1038/s41598-019-50747-3. 

M. Ooms, T. Tsujikawa, T.G. Lohith, S.N. Mabins, S.S. Zoghbi, A. Sumitomo, H. Jaaro-Peled, Y. Kimura, S. Telu, V.W. Pike, T. Tomoda, R.B., A. Sawa, M. Fujita, [11C](R)-Rolipram positron emission tomography detects Innis DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice. J. Cereb. Blood Flow Metab. (2019) 39, 1306-1313. DOI:10.1177/0271678X18758997.