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Transforming the understanding
and treatment of mental illnesses.

Celebrating 75 Years! Learn More >>

Adult Pathophysiology and Biological Interventions Development Branch


The Adult Pathophysiology and Biological Interventions Branch supports programs of research aimed at understanding the brain basis of mental disorders. Specifically supported are multidisciplinary studies with human and model systems on the genetic, molecular, cellular, circuit, and systems levels of brain function designed to elucidate the pathophysiology of mental disease and to translate these findings to clinical diagnosis, treatment, and prevention strategies. These approaches are applied to the entire spectrum of mental disorders. The branch’s five programs address three of the Institute’s four Strategic Objectives in the NIMH Strategic Plan for Research:

  • Define the mechanisms of complex behaviors
  • Chart mental illness trajectories to determine when, where, and how to intervene
  • Strive for prevention and cures

Branch Chief

Steven J. Zalcman, M.D.
6001 Executive Boulevard, Room 7123, MSC 9632