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Transforming the understanding
and treatment of mental illnesses.

Workshop: Neurofeedback Intervention Development: Opportunities and Challenges

Date

May 2, 2024

Location

Virtual

Overview

This workshop convened researchers and federal officials to review the state of the science for neurofeedback (NF) intervention development for mental disorders, with an emphasis on real time fMRI approaches. The program highlighted recent developments in both early treatment development and later efficacy and effectiveness trials, as well as regulatory issues relevant to the approval and implementation of device-based interventions like NF. Panel presentations and discussion aided in identifying new opportunities and challenges for NF development. The workshop was free and open to the scientific community and the public.

Recordings

Read the transcript.

Welcome and Opening Remarks 
Christopher Sarampote, Ph.D., Chief, Biomarker and Intervention Development for Childhood Onset Mental Disorders, NIMH
Michelle Hampson, Ph.D., Professor of Radiology and Biomedical Imaging, Yale University

Session 1: Early-Stage Studies of Target Engagement and Task Development

Early Stage rtfMRI Neurofeedback: Designing Experiments for Target Engagement 
Stephen LaConte, Ph.D., Associate Professor of Biomedical Engineering, Virginia Tech

Exploring Mechanistic Pathways: Neurofeedback and Precision Interventions vs. Real-Time Neuroimaging 
Masaya Misaki, Ph.D., Associate Investigator, Laureate Institute for Brain Research

Early-Stage Development of fMRI Neurofeedback: Promises and Challenges 
Michelle Hampson, Ph.D., Professor of Radiology and Biomedical Imaging, Yale University
Moderator: Christopher Sarampote, Ph.D., Chief, Biomarker and Intervention Development for Childhood Onset Mental Disorders, NIMH

Session 2: Efficacy and Effectiveness Trials of Neurofeedback for Psychiatric Illness

Personalized Network-Based Feedback & Neuromodulation in Psychiatric Disorders 
Susan Whitfield-Gabrieli, Ph.D., Professor of Psychology, Northeastern University

How to Hit a Moving Target 
Karina Quevedo, Ph.D., Associate Professor of Psychiatry and Behavioral Sciences, University of Minnesota

Efficacy and Beyond: Opportunities and Challenges of Moving rtfMRI-nf into the Clinic 
Kymberly Young, Ph.D., Associate Professor of Psychiatry, University of Pittsburgh
Moderator: Alexander Talkovsky, Ph.D., Chief, Anxiety Disorders and Mood Disorders Research Programs, NIMH

Read the transcript.

Session 3: Regulatory Issues and Implementation of Neurofeedback in Health Systems

Crossing the Bridge from Idea to Biomarker 
Talma Hendler, M.D., Ph.D., Professor of Physiology and Pharmacology and Psychiatry, Tel Aviv University

Regulatory Considerations for Neurofeedback 
Doe Kumsa, Ph.D., Senior Reviewer, Center for Devices and Radiological Health, United States Food and Drug Administration
Anita Bajaj, M.D., M.P.H., Medical Officer, Center for Devices and Radiological Health, United States Food and Drug Administration
Moderator: Sarah H. Lisanby, Ph.D., Director, Division of Translational Research, NIMH
Discussant: Luke Stoeckel, Ph.D., Program Director, Mechanistic and Translational Decision Science, National Institute on Aging

Sponsored by

National Institute of Mental Health, Division of Translational Research (DTR).