Skip to main content

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Transforming the understanding
and treatment of mental illnesses.

Genetic Epidemiology Research Branch (GEB-SDGE)

Research Interests

Mood and anxiety disorders that GEB researches include

  • Major depression
  • Bipolar disorder (manic depression)
  • Generalized anxiety disorder (GAD)
  • Social anxiety disorder/social phobia
  • Panic disorder
  • Obsessive-compulsive disorder (OCD)
  • Post-traumatic stress disorder (PTSD) 

The major research goals of GEB are

  • To conduct studies of families to identify aspects of mental disorders that are inherited;
  • To determine the reasons why mood and anxiety disorders may exist in association with other mental disorders (e.g., alcoholism, substance abuse) and medical disorders (migraine);
  • To identify the early expression of mental disorders in the population by following children of parents with these disorders;
  • To conduct pilot studies of programs aimed at preventing mood and anxiety disorders in youth;
  • To develop and apply study designs and statistical methods to identify how an interaction of genes and the environment contribute to mental disorders. Studies include half-siblings, step-siblings, children of twins, and migrant studies (i.e., people who have moved from one geographic area to another).