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Section on Molecular Neuroscience Section on Molecular Neuroscience

Selected Publications

VGLUT-VGAT expression delineates functionally specialised populations of vasopressin-containing neurones including a glutamatergic perforant path-projecting cell group to the hippocampus in rat and mouse brain . Zhang L, Hernández VS, Zetter MA, Eiden LE. J Neuroendocrinol. 2020;32(4):e12831. doi:10.1111/jne.12831. Epub 2020 Feb 13. PMID: 31944441

Impact of PACAP and PAC1 receptor deficiency on the neurochemical and behavioral effects of acute and chronic restraint stress in male C57BL/6 mice.  Mustafa T, Jiang SZ, Eiden AM, Weihe E, Thistlethwaite I, Eiden LE. Stress. 2015;18(4):408-418. doi:10.3109/10253890.2015.1025044. Epub 2015 Sep 4. PMID: 25853791

Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells . Emery AC, Eiden MV, Mustafa T, Eiden LE. Sci Signal. 2013 Jun 25;6(281):ra51. doi: 10.1126/scisignal.2003993. PMID: 23800469

PACAP controls adrenomedullary catecholamine secretion and expression of catecholamine biosynthetic enzymes at high splanchnic nerve firing rates characteristic of stress transduction in male mice . Stroth N, Kuri BA, Mustafa T, Chan SA, Smith CB, Eiden LE. Endocrinology. 2013 Jan;154(1):330-9. doi: 10.1210/en.2012-1829. Epub 2012 Dec 7. PMID: 23221599

PACAP-deficient mice show attenuated corticosterone secretion and fail to develop depressive behavior during chronic social defeat stress . Lehmann ML, Mustafa T, Eiden AM, Herkenham M, Eiden LE. Psychoneuroendocrinology. 2012 Oct 11. pii: S0306-4530(12)00321-6. doi: 10.1016/j.psyneuen.2012.09.006. [Epub ahead of print] PMID: 23062748.

Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor . Emery AC, Eiden LE. FASEB J. 2012 Aug;26(8):3199-211. doi: 10.1096/fj.11-203042. Epub 2012 Apr 24. PMID: 22532442.

Pituitary adenylate cyclase-activating polypeptide controls stimulus-transcription coupling in the hypothalamic-pituitary-adrenal axis to mediate sustained hormone secretion during stress . Stroth N, Liu Y, Aguilera G, Eiden LE. J Neuroendocrinol. 2011 Oct;23(10):944-55. doi: 10.1111/j.1365-2826.2011.02202.x. PMID: 21824204.

The host range of gammaretroviruses and gammaretroviral vectors includes post-mitotic neural cells . Liu XH, Xu W, Russ J, Eiden LE, Eiden MV. PLoS One. 2011 Mar 28;6(3):e18072. doi: 10.1371/journal.pone.0018072. PMID: 21464894.

PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells . Mustafa T, Walsh J, Grimaldi M, Eiden LE. Cell Signal. 2010 Oct;22(10):1420-6. doi: 10.1016/j.cellsig.2010.05.005. Epub 2010 May 12. PMID: 20471475.