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Molecular Imaging Branch (MIB)

2022 Publications

Full Refereed Papers

A. Boyle, A. Navarez, J. Tong, S.S. Zoghbi, V.W. Pike, R.B. Innis, N. Vasdev, Repurposing [11C]MC1 for PET imaging of cyclooxygenase-2 in colorectal cancer xenograft mouse models. Mol. Imag. Biol. (2022) 24, 366-370. DOI:10.1007/s11307-021-01675-0. 

J.-H. Lee, F.G. Siméon, J.-S. Liow, C. L. Morse, R.L. Gladding, J.A. Montero Santamaria, I.D. Henter, S.S. Zoghbi, V.W. Pike, R.B. Innis, In vivo evaluation of six analogs of 11C-ER176 as candidate 18F-labeled radioligands for translocator protein 18 kDa (TSPO). J. Nucl. Med. (2022) 63, 1252-1258. DOI:10.2967/jnumed.121.263168. 

K. Smart, M.-Q. Zheng, H. Ahmed, H. Fang, Y. Xu, L. Cai, D. Holden, M. Kapinos, Z. Felchner, J.R. Ropchan, G. Tamagnan, R.B. Innis, V.W. Pike, S.M. Ametamey, Y. Huang, R.E. Carson, Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in vivo in non-human primates: (R)-[11C]-NR2B-Me, (R)-[18F]-OF-Me-NB1, and (S)-[18F]-OF-NB1. J. Cereb. Blood Flow Metab. (2022) 42, 1398-1409. DOI:10.1177/0271678x221084416. 

M. Viviano, E. Barresi, F.G. Siméon, B. Costa, S. Taliani, F. Da Settimo, V.W. Pike, S. Castellano, Essential principles and recent progress in the development of TSPO PET ligands for neuroinflammation imaging. Curr. Med. Chem. (2022) 29, 4862-4890. DOI:10.2174/0929867329666220329204054 

Y. Wakabayashi, P. Stenkrona, R. Arakawa, X. Yan, M.G. Van Buskirk, M.D. Jenkins, J.A. Montero Santamaria, K.P. Maresca, A. Takano, J.S. Liow, T.A. Chappie, A. Varrone, S. Nag, L. Zhang, Z.A. Hughes, C.J. Schmidt, S.D. Doran, A. Mannes, P. Zanotti-Fregonara, M. Ooms, C. L. Morse, S.S. Zoghbi, C. Halldin, V.W. Pike, R.B. Innis, First-in-human evaluation of 18F-PF-06445974, a PET radioligand that preferentially labels phosphodiesterase-4B. J. Nucl. Med. (2022) 63, 1919-1924. DOI:10.2967/jnumed.122.263838. 

H.U. Shetty, C.L. Morse, V.W. Pike, Tandem mass spectrometry as an independent method for corroborating fluorine-18 radioactivity measurements in positron emission tomography. ACS Measurement Science Au. (2022) 2, 370-376. DOI:10.1021/acsmeasuresciau.2c00018. 

B.V. Kenou, L.S. Manly, S.B. Rubovits, S.A. Umeozulu, M.G. Van Buskirk, A.S. Zhang, V.W. Pike, P. Zanotti-Fregonara, I.D. Henter, R. B. Innis, Cyclooxygenases as Potential PET Imaging Biomarkers to Explore Neuroinflammation in Dementia. J. Nucl. Med. (2022) 63, 53s-59s. DOI:10.2967/jnumed.121.263199.