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Anti-Retroviral Therapy-Mediated Mental Health Side Effects Workshop


September 12, 2018


Rockville, MD

Sponsor(s): NIMH Division of AIDS Research

The NIMH Division of AIDS Research convened a workshop focused on the neuropsychiatric side effects of Antiretroviral Therapy (ART), and the potential for ART-mediated neurological toxicity when used across the lifespan of HIV.

The NIMH Division of AIDS Research gathered distinguished investigators to collectively focus on understanding the mechanisms of Antiretroviral Therapy (ART) on neuropsychiatric side effects and neurological toxicity when used across the lifespan on individuals living with HIV. The combination of drugs within ART regimens are known to be vital and highly efficacious at targeting different steps in the life cycle of HIV, yet the ART exposure found to potentially induce neuropsychiatric symptoms and neurological toxicities in selected cases may require further understanding of underlying co-morbid medical conditions, exposure to other medications, and biological factors. Participants emphasized a need for next-generation HIV medications with fewer neuropsychiatric side effects.