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The National Institute of Mental Health archives materials that are over 4 years old and no longer being updated. The content on this page is provided for historical reference purposes only and may not reflect current knowledge or information.

Treatment-Resistant Depression & the Neurobiology of Suicide

Date and Time

December 6, 2018



Sponsor(s): NIMH Division of Intramural Research Programs (IRP)

Join experts from the National Institute of Mental Health (NIMH) for a workshop on treatment-resistant depression and the neurobiology of suicide.


An Update on the Research and Management of Treatment-Resistant Depression
Speaker: Carlos A. Zarate, M.D.

  • To understand the causes of treatment-resistant depression.
  • To become familiar with research on treatment-resistant depression, particularly with ketamine and other glutamatergic modulators.
  • To understand research on biomarkers of treatment response.

An Update on the Neurobiology of Suicide
Speaker: Elizabeth Ballard, Ph.D.

  • Provide an overview of recent research on the neurobiology and epidemiology of suicide
  • Present research on potential interventions with rapid impact on suicidal thoughts

Major Depression: A Brain and Systemic Illness
Speaker: Bashkim Kadriu, M.D.

  • To understand the effect of depression in the brain and systemic illness. 
  • To understand the effect of depression in increasing risk on medical systemic illnesses. 
  • How current therapeutics affect medical illnesses.  
  • To Understand the effects of novel fast-acting antidepressants in treatment of medical systemic illnesses. 

Use of Non-invasive Brain Stimulation to Remediate Depression
Speaker: Bruce Luber, Ph.D.

  • To present our ongoing research using both non-convulsive and convulsive brain stimulation to modulate targeted brain networks involved with treatment-resistant depression.

Ketamine: A Novel Agent for Treatment-Resistant Depression
Speaker: Elia Acevedo, MD

  • Provide an overview of ketamine research and its promising results as a fast-acting antidepressant
  • To understand potential safety concerns and side effects associated with the use of ketamine for the treatment of depression.

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