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Transforming the understanding
and treatment of mental illnesses.

Section on Development and Affective Neuroscience (SDAN)

Publications

Section on Development and Affective Neuroscience: Publications

The researchers and staff in the Section on Development and Affective Neuroscience regularly share the results of research through publications in the world’s premier scientific journals. Read the articles below to learn more about the exciting research taking place in SDAN.

Publication: : Cover image of Biological Psychiatry, Volume 89, issue 6. The cover image shows a female healthcare worker standing with her hands in the shape of a heart.

Shared and Anxiety-Specific Pediatric Psychopathology Dimensions Manifest Distributed Neural Correlates

Findings revealed two replicable types of clinical variates, one related to multiple symptom dimensions and a second relatively specific to anxiety. Both types involved a multitude of broadly distributed, weak brain connections as opposed to strong connections encompassing known resting-state networks.

Publication: First page of the article, including keywords and abstract.

Childhood Antecedents and Risk for Adult Mental Disorders

The burden of mental disorders rivals most other health problems (Collins et al. 2011). Although recognition of this burden has intensified the search for novel treatments, early promise remains unfulfilled. Steady progress in genetics and neuroscience has not improved outcomes over many decades (Insel 2009). Discoveries generating currently available, widely employed treatments occurred decades before recent advances in genetics and neuroscience.

Publication: The Risk for Early-Adulthood Anxiety and Depressive Disorders in Adolescents With Anxiety and Depressive Disorders

The Risk for Early-Adulthood Anxiety and Depressive Disorders in Adolescents With Anxiety and Depressive Disorders

Various studies find relationships among anxiety and depressive disorders of adolescence and adulthood. This study prospectively examines the magnitude of longitudinal associations between adolescent and adult anxiety or depressive disorders.

Publication: Fluvoxamine for the treatment of anxiety disorders in children and adolescents

Fluvoxamine for the treatment of anxiety disorders in children and adolescents

Drugs that selectively inhibit serotonin reuptake are effective treatments for adults with mood and anxiety disorders, but limited data are available on the safety and efficacy of serotonin-reuptake inhibitors in children with anxiety disorders.

Publication: Infant behavioral inhibition predicts personality and social outcomes three decades later

Infant behavioral inhibition predicts personality and social outcomes three decades later

Children show different temperamental styles early in development. Whether temperament predicts who children become as adults and how early we can predict these outcomes have been long-standing questions of interest to the scientific and public community. The current study used rigorous methods to characterize an inhibited temperament by 14 mo of age in a cohort of infants and followed them for three decades.

Dr. Pine’s Publications