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ETPB in the News

Science News

Dr. Carlos Zarate – Ketamine to Combat Depression    
January 13, 2021 • Science Update

NIMH Director to Discuss Advances in Treating Major Depression   
February 14, 2020 • Press Release

NIMH’s Carlos Zarate Jr., M.D., Elected to National Academy of Medicine  
October, 22, 2020 • Institute Update

Side effects mild, brief with single antidepressant dose of intravenous ketamine   
November 15, 2019 • News Release

Shake it off – Boosting your Mood    
January 2019 • Press Release

NIMH: Ketamine-Like Hallucinogens May Offer New Hope for Treatment-Resistant Depression   
November 16, 2017 • Press Release

Ketamine Lifts Depression Via a Byproduct of its Metabolism  
May 4, 2016 • Press Release

NIH Nearly Doubles Investment in BRAIN Initiative Research  
October 13, 2016 • Press Release

Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action  
October 17, 2014 • Press Release

Imaging Biomarker Predicts Response to Rapid Antidepressant: Signals Dysfunction in Brain System Targeted by Scopolamine: Maura Furey on Scopolamine Research  
February 4, 2013 • Press Release

Webinar on Ketamine and Next Generation Therapies Featuring NIMH’s Carlos A. Zarate, M.D.  
August 6, 2013• Science Update

Brain Signal ID's Responders to Fast-Acting Antidepressant: Biomarkers Help Pinpoint Mechanisms, Predict Outcomes   
August 3, 2012 • News Release

Experimental Agent Briefly Eases Depression Rapidly in Test  
December 11, 2012 • Press Release

Rapid Antidepressant Action of Common Medication Confirmed by Repeat Trial: Maura Furey on Scopolamine Research  
May 4, 2010• Science Update

Study Shows Possibilities for Predicting How Patients Will Respond to Antidepressants  
July 22, 2010 • Science Update

Experimental Medication Lifts Depression Symptoms in Bipolar Disorder Within an Hour  
August 6, 2010• Science Update

Millisecond Brain Signals Predict Response to Fast-Acting Antidepressant: Electromagnetic Biomarker Could Minimize Trial-and-Error Prescribing  
October 2, 2008 • Press Release

Research Highlights


The need for speed: A new approach to treating depressive disorders   
NIH Intramural Research Program Research 

From Despair to Hope in Hours   
NIH Intramural Research Program Research in Action

Ketamine: A New (and Faster) Path to Treating Depression  
NIMH Strategic Plan Highlight

Depression Research: Relief in Hours?   
Summer 2007 Issue • MedlinePlus

Brain Scans Give Clues to Antidepressant's Effects   
NIH News in Health

Bipolar Disorder

Major Ups and Downs: Bipolar Disorder Brings Extreme Mood Swings   
NIH News in Health


White House Mental Health Virtual Event: How Science Offers Hope for Treatment-Resistant Depression  Carlos Zarate [July 22, 2022]

Astute Clinician Lecture: “Relief from severe depression and suicidal ideation within hours: from synapses to symptoms ” [Nov 24, 2015]

Ketamine and Depression: From Despair to Hope in Hours : Carlos Zarate, NIH Clinician Scientist [Apr 4, 2013]



A New Approach to using Transcranial Magnetic Stimulation (TMS) in Depression, Bruce Luber, Ph.D. 

Depression and TMS, Bruce Luber, PhD.,   
American Academy for the Advancement of Science

Between Thought and Therapy: Translating Neurobiology Research into Treatments 

Social Media

NIMH Twitter Chat: Depression  
In recognition of National Depression Screening Day, NIMH hosted a Twitter chat on depression, a common but serious mood disorder. This chat covered the signs and symptoms, risk factors, and treatments for depression. Two experts, Dr. Lawrence Park and Dr. Bashkim Kadriu, were available to answer questions.[Oct 11, 2018]

NIH Intramural Reddit: “Ask Me Anything” with Dr. Carlos Zarate Jr. - Developing Novel Therapeutics for Depression

The National Institute of Mental Health (NIMH) and the National Institutes of Health (NIH)’s Intramural Research Program (IRP) teamed up for a Reddit “Ask Me Anything” (AMA) discussion with Dr. Carlos Zarate Jr, chief of NIMH’s Experimental Therapeutics & Pathophysiology Branch. [Nov 13, 2018]

During the Reddit AMA, Dr. Zarate answered questions from the public about current treatments for depression and the latest research efforts to develop cutting-edge therapies for the condition.

View the full AMA on Reddit  , or for a summary, visit the NIH’s Intramural Blog: Shedding Light on the Deep Darkness of Depression  [Nov 15, 2018]



Treatment-Resistant Depression & the Neurobiology of Suicide 

Experts from the ETPB team hosted a workshop titled “ Treatment-Resistant Depression & the Neurobiology of Suicide ” [December 6, 2018]

Media Interviews

Is Shock Therapy Making a Comeback?   
CBS News: 60 Minutes, May 13, 2018

Depression Treatments Inspired By Club Drug Move Ahead In Tests   
NPR, May 28, 2015

The Search for a 'Safer' Ketamine  -- Can glutamate drugs treat the worst cases of depression -- and keep pharma in psychiatry?   
MEDPAGE Today, Nov 2, 2015

Brain Study Seeks Roots of Suicide   
Scientific American, Nature: Mind, November 25, 2015

Ketamine and Next Generation Therapies - Carlos Zarate, M.D.   
Brain & Behavior Research Foundation , August 14, 2013

Could A Club Drug Offer 'Almost Immediate' Relief From Depression?  [Part 1]  
NPR Morning Edition, January 30, 2012

'I Wanted To Live': New Depression Drugs Offer Hope For Toughest Cases  ;[Part 2]  
NPR Morning Edition, January 31, 2012

Ketamine Relieves Bipolar Depression, Suicidal Thoughts in Less Than an Hour   
PsychCentral, May 31, 2012

Carlos Zarate MD, 2011 Bipolar Mood Disorders Prize   
Brain & Behavior Research Foundation , November 15, 2011

Breast Cancer Med Reduces Mania   
PsychCentral, September 12, 2007