Data Downloads

These data or code are provided as-is, and without warranty, for scientific and educational use only. The user acknowledges that these data/code will be used only for research purposes; that the user is in compliance with all applicable state, local, and federal laws or regulations and institutional policies regarding human subjects and genetics research; that secondary distribution of the data/code without independent download by secondary parties is prohibited; and that the user will cite the relevant publication(s) in any communications or publications arising directly or indirectly from these data/code.

A population-specific reference panel empowers genetic studies of Anabaptist populations . Liping Hou, Rachel L. Kember, Jared C. Roach, Jeffrey R. O’Connell, David W. Craig, Maja Bucan, William K. Scott, Margaret Pericak-Vance, Jonathan L. Haines, Michael H. Crawford, Alan R. Shuldiner, Francis J. McMahon. Scientific Reports, 2017. IMPUTATION SERVER UNDER DEVELOPMENT. PLEASE CHECK BACK FOR LINK.

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Liping Hou, Sarah E Bergen, Nirmala Akula . . . Francis J McMahon. Hum Mol Genet. 2016 Jun 21. pii: ddw181. http://hmg.oxfordjournals.org/content/early/2016/06/20/hmg.ddw181.abstract 

Please cite this paper if you use these results. Those using data from the NIMH sample should cite the NIMH Genetics Initiative Bipolar Disorder Consortium by use of the language specified in the Distribution Agreement from the NIMH Center for Collaborative Genetic Studies.

• BP_GWAS_meta_results.tar.gz

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.  Akula N, Barb J, Jiang X, Wendland JR, Choi KH, Sen SK, Hou L, Chen DT, Laje G, Johnson K, Lipska BK, Kleinman JE, Corrada-Bravo H, Detera-Wadleigh S, Munson PJ, McMahon FJ.. Mol Psychiatry. 2014 Jan 7

Please cite the above article if you use these files.

• Contact Dr. Nirmala Akula at akulan@mail.nih.gov to obtain a zip file of the data.

Chen DT, et al. Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol Psychiatry. 2011 Dec 20 .

Please cite this paper if you use these data. In addition, please cite the NIMH Genetics Initiative Bipolar Disorder Consortium by use of the language specified in the Distribution Agreement from the NIMH Center for Collaborative Genetic Studies.

• Chen DT et al, 2011 Data

Akula N, et al. A network-based approach to prioritize results from genome-wide association studies. PLoS One. 2011;6(9):e24220. Epub 2011 Sep 6 .

Please cite this paper if you use the code.

• NIMMI_GWAS_Network_Analysis
• NIMMI_scriptsForPermutation

Summary results from: McMahon FJ, et al. Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet. 2010; 42:128-31, published online 17 Jan 2010 .

Please cite this paper if you use these data. In addition, those using data from the NIMH sample should cite the NIMH Genetics Initiative Bipolar Disorder Consortium by use of the language specified in the Distribution Agreement from the NIMH Center for Collaborative Genetic Studies.

Supplemental Table 1 Summary results from meta-analysis of bipolar and unipolar case-control samples. Headers correspond to standard output from METAL.