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Transforming the understanding
and treatment of mental illnesses.

Progress for Goal 2

Learn about the progress NIMH has made toward Goal 2 of the NIMH Strategic Plan for Research: Examine Mental Illness Trajectories Across the Lifespan.


illustration of human brain seen from above
Brain Activity Patterns After Trauma May Predict Long-Term Mental Health

The way a person’s brain responds to stress following a traumatic event, such as a car accident, may help to predict their long-term mental health outcomes, according to NIMH-supported research.

line drawing illustration of human brain
Mapping ‘Imbalance’ in Brain Anatomy Across the Lifespan

Researchers in the NIMH Intramural Research Program have developed a new way to measure the degree to which the proportions of an individual person’s brain differ from the proportions typically seen in the broader population. This technique yields new insights into brain development and offers tools for further study.

a young woman looks pensively out a window
Study Identifies Risk Factors for Elevated Anxiety in Young Adults During COVID-19 Pandemic

A new study has identified early risk factors that predicted heightened anxiety in young adults during the coronavirus pandemic.

outline art of male and female human figures
NIMH Part of Collaborative Effort to Advance Early Intervention for Individuals at Risk of Developing Schizophrenia

NIMH has joined with other NIH Institutes in launching an new Accelerating Medicines Partnership focused on advancing the development of better ways to identify and treat those at clinical high risk for psychosis.

photo of residential street with bright street lights at dusk
Outdoor Light Linked with Teens’ Sleep and Mental Health

A large-scale study of U.S. teens shows associations between outdoor, artificial light at night and health outcomes.

Identifying Practices for Reducing Incarceration of Those with Mental Illnesses—A Study of “Stepping Up”
Identifying Practices for Reducing Incarceration of Those with Mental Illnesses—A Study of “Stepping Up”

According to a 2017 report by the Bureau of Justice Statistics, approximately two-thirds of female inmates in prisons and jails and around a third of men in prisons and jails report having been diagnosed as having mental health disorder by a mental health professional.

Using Technology to Help Predict Binge and Purge Episodes in People with Eating Disorders
Using Technology to Help Predict Binge and Purge Episodes in People with Eating Disorders

In binge-eating disorder and bulimia nervosa, people experience recurrent and frequent episodes in which they eat unusually large amounts of food and feel a sense of loss of control.

Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults
Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults

The use of right unilateral ultrabrief pulse (RUL-UB) electroconvulsive therapy (ECT) in combination with the antidepressant venlafaxine to treat depression in elderly patients is well tolerated and results in minimal neurocognitive side effects, according to a new NIH-funded study published in the American Journal of Geriatric Psychiatry.

Transforming Mental Health Care Through ALACRITY
Transforming Mental Health Care Through ALACRITY

In 2018, 11.4 million adults in the United States experienced a serious mental illness, such as schizophrenia-spectrum disorders, severe bipolar disorder, and severe depression.