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Adults: Schizophrenia

Join a Research Study: Enrolling nationally from around the country

A Study of Schizophrenia and the Brain: A Six-month Inpatient Evaluation Study

The National Institute of Mental Health in Bethesda, Maryland, invites qualifying adults who have been diagnosed with schizophrenia or schizoaffective disorder to participate in an inpatient research study at the NIH Clinical Center. In this study, researchers will be evaluating how the brain works in individuals diagnosed with schizophrenia to better understand the underlying causes of this illness.

This study is usually six months long and generally has three phases: The first phase involves a thorough evaluation of diagnosis, medications, and treatment. The second phase includes evaluations during periods on and off standard medications, with each period ranging from four to six weeks. The third phase focuses on stabilization, treatment, and discharge planning.

Evaluations include a variety of medical, cognitive, neurological, and neurocognitive assessments. Advanced neuroimaging techniques (e.g., MRI, MEG, and PET) are used along with specialized cognitive tests designed to understand specific functions of the brain.

To find out if you qualify, email NIMH or call 1-301-435-8970 (1-888-674-6464) [TTY: 1-866-411-1010].

Join a Research Study: Enrolling nationally from around the country

The NIMH Genetic Study of Schizophrenia

If you or someone in your family is 18 years old or older and has been diagnosed with schizophrenia or schizoaffective disorder (depressed type), you may be able to participate in a genetic study that looks for genes in families. In order for family members to participate, the person with schizophrenia must be willing and able to participate. Eligible family members participate in an interview and contribute a sample of blood for genetic analysis. If you have schizophrenia, and if possible, your sibling, you may qualify to participate in this study. There is no change in medication involved.

The study involves simple cognitive tests and some MRI scans (no radiation). All testing is completed free of charge and there is compensation for each family member's participation in the study. Travel and lodging assistance is also available.

Scientists believe that the identification of susceptibility genes is key to understanding the molecular pathways of this disease so that better treatments and preventive methods can be developed in the future.

To find out if you qualify, email NIMH or call 1-301-435-8970 (1-888-674-6464) [TTY: 1-866-411-1010].