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The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Transforming the understanding
and treatment of mental illnesses.

Adults: Bipolar Disorder

A Family Study, What Impacts Mood, Sleep, and Energy?

Enrolling locally from the Washington, D.C. metro region

This research study is enrolling people to help us understand how physical activity, daily rhythms, and light affect mental health. 

Depression & Transcranial Electric Stimulation Therapy (TEST)

Enrolling nationally from around the country

Researchers are testing a new type of investigational non-invasive brain stimulation to see if it is safe and potentially helpful to treat depression symptoms.

Investigating the Genetics of Bipolar Disorder in those affected and their family members

Enrolling nationally from around the country

Researchers are looking for genes that may affect a person's chances of developing bipolar disorder. You can participate in this research study if you are over 18, have a bipolar diagnosis, or have a family member with bipolar disorder.

NIMH Family Study of Health and Behavior

Enrolling locally from the Washington, D.C. metro region

The major goal of this study is to examine how mood disorders, anxiety disorders and migraine run in families. We study both genetic and environmental factors that may contribute to these conditions.

Suicide and the Brain

Enrolling nationally from around the country

National Institute of Mental Health (NIMH) researchers seek adults 18 to 70, who have a history of attempted suicide but are not currently suicidal, for a study of suicide and brain function. Participation includes up to seven days as an inpatient at the NIH Clinical Center in Bethesda, Maryland. Procedures include blood tests, medical evaluations, brain imaging, sleep studies and psychiatric interviews. Participants do not need to stop their current medications. Compensation and transportation are provided. Pregnant women and individuals with serious medical conditions are not eligible.