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Transforming the understanding
and treatment of mental illnesses.

Adults: Healthy Volunteers

Brain and Body Imaging Studies

Enrolling locally from the Washington, D.C. metro region

Several investigational studies are measuring proteins in the brain and  body using Positron Emission Tomography (PET) technology to better understand the biological basis of mental illness and to eventually pave the way for new treatments.

Brain and Body Responses to Stress Study

Enrolling locally from the Washington, D.C. metro region

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

Brain and Cognition Research Study

Enrolling locally from the Washington, D.C. metro region

Researchers are enrolling healthy volunteers for an outpatient research study to learn more about how the brain works.

Brain Changes in Fear and Anxiety Study

Enrolling locally from the Washington, D.C. metro region

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

DECIBELS: DiscovEring CortIcal BiomarkErs in Language processing in adolescents with autism spectrum disorders

Enrolling locally from the Washington, D.C. metro region

Are you a healthy young adult with no neurological, psychiatric, or general medical condition 18-25 and interested in learning more about how your brain processes language? If so, you may be eligible to participate in the pilot phase of a new research study at NIMH.

Healthy Research Volunteer Study

Enrolling locally from the Washington, D.C. metro region

People in good health are invited to participate as a research study volunteer. Study participants play a vital role in biomedical research by helping scientists advance knowledge and better understand, treat, and ultimately, improve health.

The National Institute of Mental Health (NIMH) is conducting this study to create a list of healthy research volunteers who are interested in participating in additional NIMH studies.

How Does the Covid-19 Pandemic Impact Mental Health?

Enrolling nationally from around the country

The purpose of this online study is to learn about how stressors related to the COVID-19 virus impact mental health and attention over time. We hope to better understand how people from a wide range of communities adjust their own behaviors, family lives, and daily activities to best cope with uncertainty and restrictions imposed by the pandemic.

Memories and How the Brain Works

Enrolling locally from the Washington, D.C. metro region

Researchers are enrolling healthy volunteers for an outpatient research study to learn about the brain. A part of the study evaluates how the brain activates and represents memories. Participants will watch videos created in the “1 Second Everyday App” during a brain scan (MRI) and again during a MEG (magnetoencephalography) scan.

Neural and Psychological Mechanisms of Pain Perception

Enrolling locally from the Washington, D.C. metro region

People feel different levels of pain. These differences are caused by social, cultural, and biological factors. Researchers at the National Institutes of Health are trying to better understand the different factors that impact pain and how people experience pain.

Study of the Brain, Thinking and Memory

Enrolling locally from the Washington, D.C. metro region

This part of the facial recognition study is enrolling healthy adults without psychiatric conditions, between the ages of 18 and 35, who are in good medical health, and have a bad memory for faces. The overall purpose of the study is to learn about the brain, thinking and memory in people with and without autism spectrum disorders.

The Impact of COVID-19 Pandemic on Anxiety and Motivation

Enrolling nationally from around the country

Researchers hope to better understand changes in emotional reactions and assess motivation in people during this stressful pandemic. We hope to understand the way these changes are different for people suffering from anxiety or mood disorders, and people who do not.

TMS and Brain Function

Enrolling locally from the Washington, D.C. metro region

This research study seeks healthy adult participants to explore how transcranial magnetic stimulation (TMS) affects the brain. TMS is a non-invasive method which uses a magnet placed outside the head to stimulate precise locations inside the brain.

Understanding How Ketamine Affects Brain Chemistry

Enrolling nationally from around the country

The purpose of this study is to evaluate how a dose of ketamine affects brain chemistry, and how it alleviates depression symptoms so quickly. Ketamine is a general anesthetic medication used to put people to sleep for surgery.

Understanding the brain, mood, memory, and thinking

Enrolling locally from the Washington, D.C. metro region

This research study seeks to learn about the brain, moods, memory, thinking and concentration in healthy adults and compare them to those who have HIV infections.