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Depression Evaluations for Medication and Brain Imaging Studies

Join a Research Study: Enrolling nationally from around the country

To find out if you qualify, email NIMH or call 1-877-646-3644 (1-877-MIND-NIH) [TTY: 1-866-411-1010].

These inpatient and outpatient studies investigate the brain and experimental medications (such as ketamine and diazoxide) to rapidly reduce depressive symptoms.

Participation may include outpatient visits or inpatient stays of up to 12 weeks at the NIH Clinical Center, Bethesda, MD. Procedures may include: tapering off current psychiatric medications, a medication-free period, oral or intravenous medication versus placebo, and brain scans. Participants must be ages 18 to 70 and free of serious medical conditions.

First steps to participate include, calling NIMH, learning study details, asking about your eligibility, and consenting to participate. There is no cost to participate. These studies may enroll eligible participants from across the USA. Travel arrangements and compensation are provided.