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RDoC Matrix

Important Notes on the Matrix

Read these notes first if you are new to the RDoC Matrix.

Negative Valence Systems

Construct/Subconstruct		Genes	Molecules	Cells	Circuits	Physiology	Behavior	Self-Report	Paradigms
Acute Threat ("Fear")		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Potential Threat ("Anxiety")		Elements	Elements	Elements	Elements	Elements			Elements
Sustained Threat			Elements	Elements	Elements	Elements	Elements
Loss		Elements	Elements		Elements	Elements	Elements	Elements
Frustrative Nonreward		Elements	Elements		Elements		Elements	Elements	Elements

Positive Valence Systems

Construct/Subconstruct		Genes	Molecules	Cells	Circuits	Physiology	Behavior	Self-Report	Paradigms
Approach Motivation	Reward Valuation		Elements		Elements			Elements	Elements
	Effort Valuation / Willingness to Work		Elements		Elements			Elements	Elements
	Expectancy / Reward Prediction Error		Elements		Elements	Elements	Elements	Elements	Elements
	Action Selection / Preference-Based Decision Making				Elements				Elements
Initial Responsiveness to Reward Attainment		Elements	Elements		Elements		Elements	Elements	Elements
Sustained/Longer-Term Responsiveness to Reward Attainment			Elements		Elements	Elements	Elements	Elements	Elements
Reward Learning		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Habit		Elements	Elements	Elements	Elements		Elements	Elements	Elements

Cognitive Systems

Construct/Subconstruct		Genes	Molecules	Cells	Circuits	Physiology	Behavior	Self-Report	Paradigms
Attention		Elements	Elements	Elements	Elements	Elements	Elements		Elements
Perception	Visual Perception	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Auditory Perception	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Olfactory/Somatosensory/Multimodal/Perception								Elements
Declarative Memory		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Language		Elements			Elements	Elements	Elements	Elements	Elements
Cognitive Control	Goal Selection; Updating, Representation, and Maintenance ⇒ Focus 1 of 2 ⇒ Goal Selection				Elements			Elements	Elements
	Goal Selection; Updating, Representation, and Maintenance ⇒ Focus 2 of 2 ⇒ Updating, Representation, and Maintenance	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Response Selection; Inhibition/Suppression ⇒ Focus 1 of 2 ⇒ Response Selection	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Response Selection; Inhibition/Suppression ⇒ Focus 2 of 2 ⇒ Inhibition/Suppression	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Performance Monitoring	Elements	Elements		Elements	Elements	Elements	Elements	Elements
Working Memory	Active Maintenance	Elements	Elements	Elements	Elements	Elements			Elements
	Flexible Updating	Elements	Elements	Elements	Elements	Elements			Elements
	Limited Capacity	Elements	Elements		Elements	Elements			Elements
	Interference Control	Elements	Elements	Elements	Elements	Elements			Elements

Social Processes

Construct/Subconstruct		Genes	Molecules	Cells	Circuits	Physiology	Behavior	Self-Report	Paradigms
Affiliation and Attachment		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Social Communication	Reception of Facial Communication	Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
	Production of Facial Communication	Elements	Elements		Elements	Elements	Elements	Elements	Elements
	Reception of Non-Facial Communication	Elements	Elements		Elements	Elements	Elements	Elements	Elements
	Production of Non-Facial Communication	Elements			Elements		Elements		Elements
Perception and Understanding of Self	Agency				Elements	Elements	Elements	Elements	Elements
Perception and Understanding of Self	Self-Knowledge			Elements	Elements	Elements	Elements	Elements	Elements
Perception and Understanding of Others	Animacy Perception				Elements	Elements	Elements		Elements
	Action Perception			Elements	Elements	Elements	Elements	Elements	Elements
	Understanding Mental States	Elements	Elements		Elements		Elements	Elements	Elements

Arousal and Regulatory Systems

Construct/Subconstruct		Genes	Molecules	Cells	Circuits	Physiology	Behavior	Self-Report	Paradigms
Arousal		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Circadian Rhythms		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements
Sleep-Wakefulness		Elements	Elements	Elements	Elements	Elements	Elements	Elements	Elements