Skip to content

RDoC Matrix

Previous Versions

  • Version 1 (saved 3/7/2016) – This is the original version of the RDoC matrix that was created from the original Domain Workshops.
  • Version 2 (saved 10/20/2016) – This version is the first major update since the original Domain Workshops, and represents a shift to the newly formatted web-interface for displaying the matrix information.
  • Version 3 (saved 5/18/2017) – This version represents updated information in the paradigms column, as a result of the recommendations from the Council Workgroup on Tasks and Measures for RDoC.

Important Notes on the Matrix

Read these notes first if you are new to the RDoC Matrix.

Negative Valence Systems

Construct/Subconstruct Genes
Notice
Molecules Cells Circuits Physiology Behavior Self-Report Paradigms
Acute Threat ("Fear") Elements Elements Elements Elements Elements Elements Elements
Potential Threat ("Anxiety") Elements Elements Elements Elements Elements Elements
Sustained Threat Elements Elements Elements Elements Elements Elements
Loss Elements Elements Elements Elements Elements Elements
Frustrative Nonreward Elements Elements Elements Elements Elements

Positive Valence Systems

Construct/Subconstruct Genes
Notice
Molecules Cells Circuits Physiology Behavior Self-Report Paradigms
Approach Motivation Reward Valuation Elements Elements Elements Elements
Effort Valuation / Willingness to Work Elements Elements Elements Elements
Expectancy / Reward Prediction Error Elements Elements Elements Elements Elements Elements
Action Selection / Preference-Based Decision Making Elements
Initial Responsiveness to Reward Attainment Elements Elements Elements Elements Elements
Sustained/Longer-Term Responsiveness to Reward Attainment Elements Elements Elements Elements Elements
Reward Learning Elements Elements Elements Elements Elements Elements Elements
Habit Elements Elements Elements Elements Elements Elements

Cognitive Systems

Construct/Subconstruct Genes
Notice
Molecules Cells Circuits Physiology Behavior Self-Report Paradigms
Attention Elements Elements Elements Elements Elements Elements
Perception Visual Perception Elements Elements Elements Elements Elements Elements Elements
Auditory Perception Elements Elements Elements Elements Elements Elements Elements
Olfactory/Somatosensory/Multimodal/Perception Elements
Declarative Memory Elements Elements Elements Elements Elements Elements Elements
Language Elements Elements Elements Elements Elements
Cognitive Control Goal Selection; Updating, Representation, and Maintenance ⇒ Focus 1 of 2 ⇒ Goal Selection Elements Elements Elements
Goal Selection; Updating, Representation, and Maintenance ⇒ Focus 2 of 2 ⇒ Updating, Representation, and Maintenance Elements Elements Elements Elements Elements Elements Elements
Response Selection; Inhibition/Suppression ⇒ Focus 1 of 2 ⇒ Response Selection Elements Elements Elements Elements Elements Elements Elements
Response Selection; Inhibition/Suppression ⇒ Focus 2 of 2 ⇒ Inhibition/Suppression Elements Elements Elements Elements Elements Elements Elements
Performance Monitoring Elements Elements Elements Elements Elements Elements
Working Memory Active Maintenance Elements Elements Elements Elements Elements
Flexible Updating Elements Elements Elements Elements Elements
Limited Capacity Elements Elements Elements Elements
Interference Control Elements Elements Elements Elements Elements

Social Processes

Construct/Subconstruct Genes
Notice
Molecules Cells Circuits Physiology Behavior Self-Report Paradigms
Affiliation and Attachment Elements Elements Elements Elements Elements Elements Elements
Social Communication Reception of Facial Communication Elements Elements Elements Elements Elements Elements Elements
Production of Facial Communication Elements Elements Elements Elements Elements
Reception of Non-Facial Communication Elements Elements Elements Elements Elements Elements
Production of Non-Facial Communication Elements Elements Elements Elements
Perception and Understanding of Self Agency Elements Elements Elements Elements
Self-Knowledge Elements Elements Elements Elements Elements Elements
Perception and Understanding of Others Animacy Perception Elements Elements Elements Elements
Action Perception Elements Elements Elements Elements Elements Elements
Understanding Mental States Elements Elements Elements Elements Elements

Arousal and Regulatory Systems

Construct/Subconstruct Genes
Notice
Molecules Cells Circuits Physiology Behavior Self-Report Paradigms
Arousal Elements Elements Elements Elements Elements Elements Elements
Circadian Rhythms Elements Elements Elements Elements Elements Elements Elements
Sleep-Wakefulness Elements Elements Elements Elements Elements Elements Elements