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and treatment of mental illnesses.

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Psychological Treatments for Youth with Severe Irritability

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

To find out if you qualify, email the study team ( or call 1-301-496-8381 [TTY: 711].

Children who enroll in our studies have irritability that significantly impacts their functioning at home, in school, and with other children. These studies seek to find out whether certain research treatments can be effective for children who are very irritable. 

Eligible children may be offered a diagnostic assessment, a new approach to cognitive behavioral therapy, or non-treatment research options. Parent and child must agree to child’s participation. Child can remain on current medications.

The studies are currently enrolling participants who are:

  • 8- to 17-years old
  • angry, irritable, easily frustrated, or tend to have explosive temper outbursts
  • in treatment with a pediatrician, psychiatrist, or therapist
  • medically healthy, and not currently suicidal, psychotic, or hospitalized

Participation includes a 1-day outpatient visit to confirm eligibility. Eligible families may choose to participate in:

  • outpatient treatment studies
  • a non-treatment study

There is no cost to participate. Compensation is provided.

To find out if you qualify, email the study team ( or call 1-301-496-8381 [TTY: 711].

Study Identifiers

  • NIMH Protocol Number: 02-M-0021
  • Study Number: 02531893 
  • NIMH Protocol Number: 15-M-0182
  • Study Number: 02531893 

Investigator(s): Melissa Brotman, Ph.D.