The Brain’s Response to Low Doses of Ketamine

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

To contact the study team email email (moodresearch@nih.gov) or call 1-877-646-3644 (1-877-MIND-NIH ) [TTY: 711].

Learn more about our current studies.

Researchers seek to compare the brains of people with and without major depression. Researchers are looking at the brain’s response to two low doses of ketamine, under investigational use for depression. This research study is enrolling adults ages 18 to 65, who do not have serious medical conditions, and do not have mood disorders.

Study participation includes visits over six- to seven-weeks (inpatient & outpatient). Study procedures may include: two low doses of ketamine infusions and two doses of matching placebo, brain scans, blood tests, sleeps studies, and transcranial magnetic stimulation (TMS) assessments.

There is no cost to participate. Compensation of up to $2,790 is provided for participation. Enrolling locally from the Washington, D.C. metro region.

Learn more about our current studies.

To contact the study team email email (moodresearch@nih.gov) or call 1-877-646-3644 (1-877-MIND-NIH ) [TTY: 711].

Study Identifiers

• NIMH Protocol Number: 17-M-0060
• ClinicalTrials.gov Study Number: 03065335 

Investigator(s): Carlos Zarate Jr, M.D.