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Human Brain Collection Core


Papers Published 2014 - 2018

Davis KN, Tao R, Li C, Gao Y, Gondre-Lewis MC, Lipska BK, et al (2016). GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders. PLoS One 11(2): e0148558.

Erben L, He MX, Laeremans A, Park E, Buonanno A (2017). A Novel Ultrasensitive In Situ Hybridization Approach to Detect Short Sequences and Splice Variants with Cellular Resolution. Mol Neurobiol.

Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, et al (2016). Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nat Neurosci 19(11): 1442-1453.

Funk AJ, Mielnik CA, Koene R, Newburn E, Ramsey AJ, Lipska BK, et al (2017). Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia. Schizophr Bull.

Gothelf D, Law AJ, Frisch A, Chen J, Zarchi O, Michaelovsky E, et al (2014). Biological effects of COMT haplotypes and psychosis risk in 22q11.2 deletion syndrome. Biol Psychiatry 75(5): 406-413.

Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, et al (2017). Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. Nat Commun 8(1): 2225.

Kaalund SS, Newburn EN, Ye T, Tao R, Li C, Deep-Soboslay A, et al (2014). Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain. Mol Psychiatry 19(12): 1258-1266.

Kundakovic M, Jiang Y, Kavanagh DH, Dincer A, Brown L, Pothula V, et al (2017). Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue. Biol Psychiatry 81(2): 162-170.

Kunii Y, Hyde TM, Ye T, Li C, Kolachana B, Dickinson D, et al (2014). Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression. Mol Psychiatry 19(2): 192-199.

Kunii Y, Zhang W, Xu Q, Hyde TM, McFadden W, Shin JH, et al (2015). CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders. Am J Psychiatry 172(11): 1122-1130.

Landefeld CC, Hodgkinson CA, Spagnolo PA, Marietta CA, Shen PH, Sun H, et al (2018). Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors. Transl Psychiatry 8(1): 72.

LaPaglia DM, Sapio MR, Burbelo PD, Thierry-Mieg J, Thierry-Mieg D, Raithel SJ, et al (2017). RNA-Seq investigations of human post-mortem trigeminal ganglia. Cephalalgia: 333102417720216.

Morita Y, Callicott JH, Testa LR, Mighdoll MI, Dickinson D, Chen Q, et al (2014). Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. J Neurosci 34(14): 4929-4940.

Mou Z, Hyde TM, Lipska BK, Martinowich K, Wei P, Ong CJ, et al (2015). Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus. Cell Rep 13(6): 1073-1080.

Numata S, Ye T, Herman M, Lipska BK (2014). DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia. Front Genet 5: 280.

Schroeder FA, Gilbert TM, Feng N, Taillon BD, Volkow ND, Innis RB, et al (2017). Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. ACS Chem Neurosci 8(3): 662-668.

Senthil G, Dutka T, Bingaman L, Lehner T (2017). Genomic resources for the study of neuropsychiatric disorders. Mol Psychiatry 22(12): 1659-1663.

Shrestha SS, Liow JS, Jenko K, Ikawa M, Zoghbi SS, Innis RB (2016). The 5-HT1A Receptor PET Radioligand 11C-CUMI-101 Has Significant Binding to alpha1-Adrenoceptors in Human Cerebellum, Limiting Its Use as a Reference Region. J Nucl Med 57(12): 1945-1948.

Turnquist C, Horikawa I, Foran E, Major EO, Vojtesek B, Lane DP, et al (2016). p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration. Cell Death Differ 23(9): 1515-1528.