Publications

Publications with HBCC Co-Authorship

Girdhar, K., et al. (2022). "Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains." Nature Neuroscience 25(4): 474-483.

Akula, N., et al. (2021). "Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders." Neuropsychopharmacology 46(7): 1364-1372.

Gregory, M. D., et al. (2021). "Neanderthal-derived genetic variation in living humans relates to schizophrenia diagnosis, to psychotic symptom severity, and to dopamine synthesis." Am J Med Genet B Neuropsychiatr Genet 186(5): 329-338.

Gregory, M. D., et al. (2021). "Neanderthal-Derived Genetic Variation is Associated with Functional Connectivity in the Brains of Living Humans." Brain Connect 11(1): 38-44.

Hegarty, C. E., et al. (2021). "Polymorphism in the ZNF804A Gene and Variation in D1 and D2/D3 Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study." Biol Psychiatry Cogn Neurosci Neuroimaging 9: S2451-9022(20)30377-3.

Liu, Q. R., et al. (2021). "Novel Human Insulin Isoforms and C alpha-Peptide Product in Islets of Langerhans and Choroid Plexus." Diabetes 70(12): 2947-2956.

Unroe, K. A., et al. (2021). "Perinatal SSRI Exposure Disrupts G Protein-coupled Receptor BAI3 in Developing Dentate Gyrus and Adult Emotional Behavior: Relevance to Psychiatric Disorders." Neuroscience 471: 32-50.

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Espeso-Gil, S., et al. (2020). "A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons." Genome Med 12(1): 19.

Han, L., et al. (2020). "Functional annotation of rare structural variation in the human brain." Nat Commun 11(1): 2990.

Hoffman, G. E., et al. (2019). "CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder." Sci Data 6(1): 180.

Huckins, L. M., et al. (2019). "Gene expression imputation across multiple brain regions provides insights into schizophrenia risk." Nat Genet 51(4): 659-674.

Dobbyn, A., et al. (2018). "Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS." Am J Hum Genet 102(6): 1169-1184.

Girdhar, K., et al. (2018). "Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome." Nat Neurosci 21(8): 1126-1136.

Gregory, M. D., et al. (2018). "A method for determining haploid and triploid genotypes and their association with vascular phenotypes in Williams syndrome and 7q11.23 duplication syndrome." BMC Med Genet 19(1): 53.

Landefeld, C. C., et al. (2018). "Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors." Transl Psychiatry 8(1): 72.

Lee, M. R., et al. (2018). "Oxytocin receptor mRNA expression in dorsolateral prefrontal cortex in major psychiatric disorders: A human post-mortem study." Psychoneuroendocrinology 96: 143-147.

Wei, S. M., et al. (2018). "Brain-derived neurotrophic factor Val(66)Met genotype and ovarian steroids interactively modulate working memory-related hippocampal function in women: a multimodal neuroimaging study." Mol Psychiatry 23(4): 1066-1075.

Wiers, C. E., et al. (2018). "Methylation of the dopamine transporter gene in blood is associated with striatal dopamine transporter availability in ADHD: A preliminary study." Eur J Neurosci 48(3): 1884-1895.

Publications Supported by HBCC Resources

Sudre, G., Gildea, D.E., Shastri, G.G. et al. (2022). “Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder.” Mol Psychiatry.

Sampath, V.P.; Singh, S.V.; Pelov, I.; Horesh, N.; Zannadeh, H.; Tirosh, O.; Erel, Y.; Lichtstein, D. (2022). “Vanadium in Bipolar Disorders—Reviving an Old Hypothesis.” Int. J. Mol. Sci. 23, 13901.

Jin, C., Lee, B., Shen, L., Long, Q., & (2022). “Alzheimer’s Disease Neuroimaging Initiative. Integrating multi-omics summary data using a Mendelian randomization framework.” Briefings in Bioinformatics 23:6

Vilor-Tejedor, N., & Guigo, R. (2022). “Brain transcriptomic profiling reveals common alterations across neurodegenerative and psychiatric disorders.”

Pourshafie, Naemeh, et al. (2022). “Altered SYNJ2BP-mediated mitochondrial-ER contacts in motor neuron disease.” Neurobiology of Disease 172: 105832.

Langston, Rebekah G., et al. (2022). “Association of a common genetic variant with Parkinson’s disease is mediated by microglia." Science Translational Medicine 14.655: eabp8869.

van den Oord, Edwin JCG, et al. (2022). "A single‐nucleus transcriptomics study of alcohol use disorder in the nucleus accumbens." Addiction Biology 28.1: e13250.

Al-Louzi, Omar, et al. (2022). "Lesion size and shape in central vein sign assessment for multiple sclerosis diagnosis: An in vivo and postmortem MRI study." Multiple Sclerosis Journal: 13524585221097560.

Chen, R., Yang, Z., Liu, J. et al. (2022). “Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants.” Genome Med 14, 53.

Chand, G. B., et al. (2022). "Differential sphingosine-1-phosphate receptor-1 protein expression in the dorsolateral prefrontal cortex between schizophrenia Type 1 and Type 2." Frontiers in Psychiatry 13: 827981.          

Hoffman, G. E., et al. (2022). "Sex differences in the human brain transcriptome of cases with schizophrenia." Biological Psychiatry 91(1): 92-101.

Liao, C., et al. (2022). "Transcriptional patterns of coexpression across autism risk genes converge on established and novel signatures of neurodevelopment." medRxiv 2022.02.28.22271620.

Logan, R. W., et al. (2022). "Sex differences in molecular rhythms in the human cortex." Biological Psychiatry 91(1): 152-162.

Park, S. W., et al. (2022). "Differential expression of gene co-expression networks related to the mTOR signaling pathway in bipolar disorder." Translational Psychiatry 12(1): 1-11.

Dong, P., Hoffman, G.E., Apontes, P. et al. (2022). “Population-level variation in enhancer expression identifies disease mechanisms in the human brain.” Nat Genet 54, 1493–1503

Sey, N.Y.A., Hu, B., Iskhakova, M. et al. (2022). “Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.” Mol Psychiatry 27, 3085–3094.

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Alver, M., et al. (2021). "Leveraging interindividual variability of regulatory activity refines genetic regulation of gene expression in schizophrenia." medRxiv 2021.10.18.21264945.         

Arasappan, D., et al. (2021). "Transcription Factor Motifs Associated with Anterior Insula Gene Expression Underlying Mood Disorder Phenotypes." Mol Neurobiol 58(5): 1978-1989.

Bristow, G. C., et al. (2021). "Sex differences in the transcription of monoamine transporters in major depression." Journal of Affective Disorders 295: 1215-1219.         

Chand, G. B., et al. (2021). "Differential sphingosine-1-phosphate receptor-1 (S1PR1) protein expressions in the dorsolateral prefrontal cortex between schizophrenia Type 1 and Type 2." bioRxiv: 2021.2005.2015.444302.

Fries, G., et al. (2021). "Epigenetic Alterations in the Hippocampus of Patients With Bipolar Disorder." Biological Psychiatry 89(9): S12-S13.       

Jin, S., et al. (2021). "Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication." Nature Metabolism 3(3): 337-351.

Panja, D., et al. (2021). "miR-936 is Increased in Schizophrenia and Inhibits Neural Development and AMPA Receptor-Mediated Synaptic Transmission." Schizophr Bull 47(6): 1795-1805.

Powell, S. K., et al. (2021). "Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk." bioRxiv: 2021.2004.2001.438094.

Rocks, D., et al. (2021). "Cell type-specific chromatin accessibility analysis in the mouse and human brain." Epigenetics 17(2): 202-219.

Yang, J., et al. (2021). "Genetic control of RNA splicing and its distinctive role in complex trait variation." DOI:10.21203/rs.3.rs-155233/v1

Fries, G. R., et al. (2020). "Accelerated hippocampal biological aging in bipolar disorder." Bipolar Disord 22(5): 498-507.

Jabbi, M., et al. (2020). "Neuro-transcriptomic signatures for mood disorder morbidity and suicide mortality." J Psychiatr Res 127: 62-74.

Moody, C. L., et al. (2020). "Adenosine Kinase Expression in the Frontal Cortex in Schizophrenia." Schizophr Bull 46(3): 690-698.

Powers, B., et al. (2020). "Sex differences in the transcription of glutamate transporters in major depression and suicide." Journal of Affective Disorders 277: 244-252.

Riggle, B. A., et al. (2020). "CD8+ T cells target cerebrovasculature in children with cerebral malaria." J Clin Invest 130(3): 1128-1138.

Singh, S. V., et al. (2020). "Na(+), K(+)-ATPase alpha Isoforms and Endogenous Cardiac Steroids in Prefrontal Cortex of Bipolar Patients and Controls." Int J Mol Sci 21(16): 5912.

Werling, D. M., et al. (2020). "Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex." Cell Rep 31(1): 107489.

Werneburg, S., et al. (2020). "Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease." Immunity 52(1): 167-182.

Absinta, M., et al. (2019). "The "central vein sign" in inflammatory demyelination: The role of fibrillar collagen type I." Ann Neurol 85(6): 934-942.

Bowen, E. F. W., et al. (2019). "DLPFC transcriptome defines two molecular subtypes of schizophrenia." Translational Psychiatry 9(1): 147.

Mansur, R. B., et al. (2019). "The effect of body mass index on glucagon-like peptide receptor gene expression in the post mortem brain from individuals with mood and psychotic disorders." European Neuropsychopharmacology 29(1): 137-146.

Phillips, J. W., et al. (2019). "A repeated molecular architecture across thalamic pathways." Nat Neurosci 22(11): 1925-1935.

Powers, B., et al. (2019). "Differential expression of glutamate transporters and monoaminergic genes in major depression and suicide." bioRxiv: 596403.