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Children: Irritability

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

A Study of Brain Function and Symptoms in Children with Severe Mood Dysregulation

This observational research study seeks to describe the moods and behaviors of irritable children. Children who enroll in our studies have irritability that significantly impacts their functioning at home, in school, and with other children.

For those that are eligible, study participation includes a one-day outpatient evaluation. There are also up to 10 follow up visits that include diagnostic assessments, questionnaires, memory and thinking tasks, computer tasks, and brain imaging. Child can remain on current medications. Parent and child must agree to child’s participation.

The studies are currently enrolling participants who are:

  • 8- to 17-years old
  • angry, irritable, easily frustrated, or tend to have explosive temper outbursts
  • in treatment with a pediatrician, psychiatrist, or therapist
  • medically healthy, and not currently suicidal, psychotic, or hospitalized

There is no cost to participate. Compensation is provided.

To find out if you qualify, email NIMH or call 1-301-496-8381 [TTY: 1-866-411-1010].

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

Psychological Treatments for Youth with Severe Irritability

Children who enroll in our studies have irritability that significantly impacts their functioning at home, in school, and with other children. These studies seek to find out whether certain research treatments can be effective for children who are very irritable. 

Eligible children may be offered a diagnostic assessment, a new approach to cognitive behavioral therapy, or non-treatment research options. Parent and child must agree to child’s participation. Child can remain on current medications.

The studies are currently enrolling participants who are:

  • 8- to 17-years old
  • angry, irritable, easily frustrated, or tend to have explosive temper outbursts
  • in treatment with a pediatrician, psychiatrist, or therapist
  • medically healthy, and not currently suicidal, psychotic, or hospitalized

Participation includes a 1-day outpatient visit to confirm eligibility. Eligible families may choose to participate in:

  • outpatient treatment studies
  • a non-treatment study

There is no cost to participate. Compensation is provided.

To find out if you qualify, email NIMH or call 1-301-496-8381 [TTY: 1-866-411-1010].