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NIH Completes Atlas of Human DNA Differences that Influence Gene Expression

Science Update

NIH researchers have completed an atlas documenting how DNA influence human gene expression.

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NIMH Releases Strategic Research Priorities Update

Institute Update

National Institute of Mental Health (NIMH) recently released its second annual update of the Strategic Research Priorities.

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RDoC Webinar - Using the RDoC Framework in Developmental Research

Science Update

NIMH’s Research Domain Criteria (RDoC) Unit hosts a webinar titled “Using the RDoC Framework in Developmental Research.”

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Life-Saving Post-ER Suicide Prevention Strategies are Cost Effective

Press Release

Three interventions designed for follow up of patients who are identified with suicide risk in hospital emergency departments save lives and are cost effective relative to usual care.

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Depression’s “Transcriptional Signatures” Differ in Men vs. Women

Science Update

Brain gene expression associated with depression differed markedly between men and women. Such divergent “transcriptional signatures” may signal divergent underlying illness processes requiring sex-specific treatments.

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RDoC Webinar - Reward Sensitivity and Depression: From Mechanism to Implementation

Science Update

NIMH’s Research Domain Criteria (RDoC) Unit, the Delaware Project, and the Association for Behavioral and Cognitive Therapies (ABCT) conduct the second webinar in a series examining the science-to-service pipeline in psychology and psychiatry.

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Scientists Give Star Treatment to Lesser-Known Cells Crucial for Brain Development

Press Release

Star-shaped support brain cells, astrocytes, growing in 3-D “organoids” in a dish develop similarly as those in human brain tissue.

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Breakthrough Method Yields Trove of Neuron Subtypes, Gene Regulators

Science Update

Scientists have discovered a trove of neuronal subtypes by identifying their unique epigenomic signatures.

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Mood Stabilizing Medications an Effective Option for Older Adults with Bipolar Disorder

Science Update

Two standard medications for bipolar disorder were effective in controlling symptoms at doses tailored to older people in a clinical trial of treatment in adults over age 60.

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Patient-Derived Support Cells Stunt Mouse Brain Development

Science Update

Support cells generated from patients with childhood onset schizophrenia stunted neural circuit development when grafted into developing mouse brains.

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