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Science News

Fast-Fail Trial Shows New Approach to Identifying Brain Targets for Clinical Treatments

Press Release

An innovative NIMH-funded trial shows that a receptor involved in the brain’s reward system may be a viable target for treating anhedonia (or lack of pleasure), a key symptom of several mood and anxiety disorders.

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Neural Signature Identifies People Likely to Respond to Antidepressant Medication

Press Release

NIH-funded research uses machine learning algorithm to predict individual response to a commonly-prescribed antidepressant.

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NIMH Scientific Director Susan Amara Selected as AAAS President-Elect

Institute Update

Susan Amara, Ph.D., scientific director of the Intramural Research Program at the National Institute of Mental Health (NIMH), has been selected to serve as president-elect of the American Association of the Advancement of Science (AAAS).

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Emergency Department Study Reveals Patterns of Patients at Increased Risk for Suicide

Press Release

A new NIMH-funded study found that people who presented to California emergency departments with deliberate self-harm or suicidal ideation had suicide rates significantly higher than those of demographically similar Californians in the year after discharge.

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Side Effects Mild, Brief with Single Antidepressant Dose of Intravenous Ketamine

Press Release

A single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression.

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NIH Awards Funding for Early Autism Screening

Institute Update

The National Institutes of Health (NIH) has awarded more than four million dollars in FY 2019 to support seven research projects aimed at developing and validating screening tools to detect signs of autism spectrum disorder in the first year of life.

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Reading the Brain’s Map: Coordinated Brain Activation Supports Spatial Learning and Decision-Making

Press Release

NIH-supported study finds that spatial “replay” in neurons may help rats learn how to navigate toward goals.

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Schizophrenia Risk Gene Linked to Cognitive Deficits in Mice

Press Release

Mice with an impaired version of one the few genes definitively linked to schizophrenia showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.

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New BRAIN Initiative Awards Accelerate Neuroscience Discoveries

Press Release

The NIH has announced its continued support for the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative by funding more than 180 new BRAIN Initiative awards, bringing the total 2019 budget for the program to more than $424 million.

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Study Reveals Sex-Based Differences in the Development of Brain Hubs Involved in Memory and Emotion

Press Release

Researchers have uncovered sex-based differences in the development of the hippocampus and amygdala—brain areas that have been implicated in the biology of several mental disorders that impact males and females differently.

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