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Transforming the understanding
and treatment of mental illnesses.

Science Updates About Disruptive Mood Dysregulation Disorder (DMDD)

sad little girl rest on swing
Characterizing Childhood Irritability Across Ages and Stages

NIMH-supported research captures expressions of irritability across developmental stages via a clinically relevant measurement tool: the MAPS Temper Loss Scale.

Father and daughter arguing over homework. Daughter looks pouty and disgruntled.
Novel Treatment Helps Children With Severe Irritability

A new study by NIMH researchers demonstrated the effectiveness, feasibility, and safety of exposure-based cognitive behavioral therapy for severe irritability and temper outbursts in children. The positive results set the foundation to continue exploring exposure therapy as a potential treatment for childhood irritability.

a somber boy wearing a backwards baseball cap looks at the camera
Understanding the Brain Mechanisms of Irritability in Youth

Researchers have identified differences in how the brains of irritable youth react to frustration, findings that could provide new paths for developing treatments for children and adolescents with severe irritability.