Skip to content

Science News About Clinical Research and Trials

Targeted E-Health HIV Intervention Reduces STIs and Sexual Risk Behaviors

Science Update

Findings from a new study suggest an electronically delivered HIV prevention intervention may be effective in reducing sexually transmitted infections (STIs) and sexual risk behaviors in young men who have sex with men.

Continue Reading

Therapy Reduces Risk in Suicidal Youth

Science Update

A recent clinical trial of a psychotherapy called dialectical behavior therapy (DBT)—which has been shown to be effective in reducing suicide-related behavior in adults—showed that DBT can also reduce suicide attempts and suicidal behavior in adolescents.

Continue Reading

Intervention Shows Promise for Treating Depression in Preschool-Aged Children

Press Release

Researchers funded by the National Institutes of Health have shown that a therapy-based treatment for disruptive behavioral disorders can be adapted and used as an effective treatment option for early childhood depression.

Continue Reading

NIH Releases First Dataset from Unprecedented Study of Adolescent Brain Development

Press Release

The National Institutes of Health released to the scientific community an unparalleled dataset from the Adolescent Brain Cognitive Development (ABCD) study.

Continue Reading

Mood Stabilizing Medications an Effective Option for Older Adults with Bipolar Disorder

Science Update

Two standard medications for bipolar disorder were effective in controlling symptoms at doses tailored to older people in a clinical trial of treatment in adults over age 60.

Continue Reading

Neuroimaging Technique May Help Predict Autism among High-Risk Infants

Press Release

Functional connectivity magnetic resonance imaging (fcMRI) may predict which high-risk, 6-month old infants will develop autism spectrum disorder (ASD) by age 2 years.

Continue Reading

Pediatrics-based Brief Therapy Outdoes Referral for Youths with Anxiety and Depression

Science Update

A streamlined behavioral therapy delivered in a pediatrics practice offered much greater benefit to youth with anxiety and depression than a more standard referral to mental health care with follow-up in a clinical trial comparing the two approaches.

Continue Reading

Recruitment Begins for Landmark Study of Adolescent Brain Development

Press Release

The study will follow the biological and behavioral development of more than 10,000 children through adolescence into early adulthood.

Continue Reading

Electroconvulsive Therapy Lifts Depression, Sustains Remission in Older Adults

Science Update

An individualized program of follow-up treatment with electroconvulsive therapy (ECT) combined with an antidepressant was effective in preventing relapse in patients 60 years and older who had had a successful initial course of treatment for severe depression.

Continue Reading

A BRIGHT Technological Future for Mental Health Trials

Science Update

Is mobile mental health research the next frontier for smartphones? Based on Dr. Patricia Areán’s pioneering BRIGHTEN study, research via smartphone app is already a reality.

Continue Reading

Team-based Treatment for First Episode Psychosis Found to be High Value

Press Release

Coordinated Specialty Care for First Episode Psychosis is Cost Effective

Continue Reading

NIH-supported NeuroBioBank Joins Autism BrainNet in Brain Donation Initiative

Press Release

Two of the world’s largest brain tissue banks unify efforts to collect and distribute a critical number of brain donations for important autism research.

Continue Reading

Team-based Treatment is Better for First Episode Psychosis

Press Release

New research shows that a team-based, coordinated specialty care treatment plan produces better outcomes than typical community care for people with first episode psychosis. Investigators also found that treatment is most effective for people who receive care soon after psychotic symptoms begin.

Continue Reading

NIH Joins Public-Private Partnership to Fund Research on Autism Biomarkers

Press Release

James McPartland, Ph.D. of Yale University will lead a new four-year $28 million Biomarkers Consortium project that aims to improve clinical evaluation of treatments for social impairment in children with autism.

Continue Reading

Pioneering NIMH Data Sharing

Science Update

NIMH’s first major effort to share clinical trial research data—established before many current data registries existed—is still doing a brisk business.

Continue Reading

Medications for Patients with First Episode Psychosis May Not Meet Guidelines

Press Release

Many patients with first-episode psychosis receive medications that do not meet guidelines. A study finds that almost 40 % of people with first-episode psychosis in community mental health clinics across the country might benefit from medication treatment changes.

Continue Reading

Largest Autism Gene Dragnet Fingers 33 Prime Suspects

Science Update

Many patients with psychosis develop health risks associated with premature death early in the course of their mental illness, researchers have found.

Continue Reading

Groundbreaking Suicide Study

Science Update

A groundbreaking study will help researchers learn more about treating people with suicidal thoughts. Nearly 20,000 patients will be able to enroll in the trial. One of the treatments being tested was developed with the help of other patients

Continue Reading

Increased Health Risks Linked to First-episode Psychosis

Press Release

Many patients with psychosis develop health risks associated with premature death early in the course of their mental illness, researchers have found.

Continue Reading

For Schizophrenia, Newer Injectables Not Necessarily Better

Science Update

Treatment adherence is a problem among people with schizophrenia, who may not take medications because they don’t perceive its need or benefit, don’t like the side effects, or forget. To combat this issue, long-acting injectable medications are administered every 2-4 weeks. But are the new forms of these drugs better than the old ones?

Continue Reading